Results 31 to 40 of about 22,312,818 (260)

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

COPD Outreach Programme Model of Care [PDF]

, 2010
The Health Service Executive Transformation Programme (2006) identified chronic disease management as a priority (HSE, 2006), and concluded that existing therapeutic models are not meeting the current and future needs of this cohort of patients.
National COPD Programme Working Group
core  

Food insecurity, feeding practices and associated factors of acute malnutrition among children under 5 years of age in a post-conflict context in the Kasai region, Democratic Republic of Congo: a community-based case-control study

BMC Nutrition
Background The Kasai region in the Democratic Republic of Congo suffered a violent conflict in 2016-17 and has been facing high household food insecurity and acute malnutrition (AM) in under 5 children ever since.
Victoire Hubert, K. Phelan, L. I. Bozama, H. Boubacar, G. Tshibangu Sakubu, B. Tshiala, Mathilde Savy, R. Becquet, C. Cazes   +8 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The impact of postpartum psychosis on partners

BMC Pregnancy and Childbirth, 2018
Background Postpartum Psychosis is a severe mental health condition following childbirth, with a psychosis and associated mood disturbance. Research to date has primarily focused on mothers’ experiences, and on identifying risk factors, aetiology, and ...
Nia Holford, Sue Channon, Jessica Heron, Ian Jones   +3 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

National Action Plan for Energy Efficiency [PDF]

, 2006
This report presents policy recommendations for creating a national commitment to energy efficiency through gas and electric utilities, utility regulators, and partner ...
National Action Plan for Energy Efficiency (U.S.)
core  

National and regional asthma programmes in Europe

European Respiratory Review, 2015
This review presents seven national asthma programmes to support the European Asthma Research and Innovation Partnership in developing strategies to reduce asthma mortality and morbidity across Europe.
Olof Selroos, Maciej Kupczyk, Piotr Kuna, Piotr Łacwik, Jean Bousquet, David Brennan, Susanna Palkonen, Javier Contreras, Mark FitzGerald, Gunilla Hedlin, Sebastian L. Johnston, Renaud Louis, Leanne Metcalf, Samantha Walker, Antonio Moreno-Galdó, Nikolaos G. Papadopoulos, José Rosado-Pinto, Pippa Powell, Tari Haahtela   +18 more
doaj   +1 more source

Action research and health system strengthening: the case of the health sector support programme in Mauritania, West Africa

Health Research Policy and Systems, 2020
Background Access to qualitative and equitable healthcare is a major challenge in Mauritania. In order to support the country’s efforts, a health sector strengthening programme was set up with participatory action research at its core.
Kirsten Accoe, Bruno Marchal, Yahya Gnokane, Dieng Abdellahi, Paul Bossyns, Bart Criel   +5 more
doaj   +1 more source