Results 61 to 70 of about 22,312,818 (260)
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
National Clinical Programme for Rare Diseases Workshop on Clinical Research in Rare Diseases
The National Clinical Programme was established in December 2013. It is an initiative of the HSE, in partnership with the Royal College of Physicians. A key objective of the Clinical Programme for Rare Diseases is to improve access for rare diseases ...
National Clinical Programme for Rare Diseases
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A study of policy process and implementation of the National Tuberculosis Programme in India. [PDF]
TB, a major public health problem in India since the 1900s, has a current prevalence of 14 million and an estimated annual mortality of 500,000 persons. Nation-wide government sponsored anti-TB public health measures introduced in 1948, developed into ...
Narayan, Thelma
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Programme report 1: September 2011 to 31 August 2012
The National Screening Service (NSS) was part of the Health Service Executive National Cancer Control Programme during the fourth year of the CervicalCheck programme 1 September 2011 to 31 August ...
Cervial Check: The National Cervial Screening Programme
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Safermeds Briefing: Update on the National Medication Safety Programme [PDF]
The National Medication Safety Programme, “Safermeds”, is one of the priority safety programmes within the HSE Quality Improvement Division. Using the HSE framework for improving quality, we will work with patients, healthcare professionals and ...
National Medication Safety Programme
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Evaluasi Program Aksi Desa Mandiri Pangan di Kabupaten Bantul
Food security is one of the main pillars of developing resilient and sustainable economic development. Food security itself refers to the availability of food and one's access to it.
Siti Zuchainah, Indri Apriliyanti
doaj +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Background The publication of Best research for best health in 2006 and the “ring-fencing” of health research funding in England marked the start of a period of change for health research governance and the structure of research funding in England.
Caldwell Sarah EM, Mays Nicholas
doaj +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source

