Results 61 to 70 of about 22,312,818 (260)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

National Clinical Programme for Rare Diseases Workshop on Clinical Research in Rare Diseases

open access: yes, 2018
The National Clinical Programme was established in December 2013. It is an initiative of the HSE, in partnership with the Royal College of Physicians. A key objective of the Clinical Programme for Rare Diseases is to improve access for rare diseases ...
National Clinical Programme for Rare Diseases
core  

A study of policy process and implementation of the National Tuberculosis Programme in India. [PDF]

open access: yes
TB, a major public health problem in India since the 1900s, has a current prevalence of 14 million and an estimated annual mortality of 500,000 persons. Nation-wide government sponsored anti-TB public health measures introduced in 1948, developed into ...
Narayan, Thelma
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Programme report 1: September 2011 to 31 August 2012

open access: yes, 2012
The National Screening Service (NSS) was part of the Health Service Executive National Cancer Control Programme during the fourth year of the CervicalCheck programme 1 September 2011 to 31 August ...
Cervial Check: The National Cervial Screening Programme
core  

Safermeds Briefing: Update on the National Medication Safety Programme [PDF]

open access: yes, 2016
The National Medication Safety Programme, “Safermeds”, is one of the priority safety programmes within the HSE Quality Improvement Division. Using the HSE framework for improving quality, we will work with patients, healthcare professionals and ...
National Medication Safety Programme
core  

Evaluasi Program Aksi Desa Mandiri Pangan di Kabupaten Bantul

open access: yesJKAP (Jurnal Kebijakan dan Administrasi Publik), 2015
Food security is one of the main pillars of developing resilient and sustainable economic development. Food security itself refers to the availability of food and one's access to it.
Siti Zuchainah, Indri Apriliyanti
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Studying policy implementation using a macro, meso and micro frame analysis: the case of the Collaboration for Leadership in Applied Health Research & Care (CLAHRC) programme nationally and in North West London

open access: yesHealth Research Policy and Systems, 2012
Background The publication of Best research for best health in 2006 and the “ring-fencing” of health research funding in England marked the start of a period of change for health research governance and the structure of research funding in England.
Caldwell Sarah EM, Mays Nicholas
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy