Results 41 to 50 of about 667,385 (261)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

open access: yesFEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

"Linguistic Structures" andl New Poem

open access: yesبازیافت, 2018
Iftikar Jalib draws on Wittgenstein for the theoretical framework ofmodern poetry. And language remains the main site of contestation. The primary objective in Jalib is to create linguistic structures which suit the demands of modern poetry.
Rubab Tabassum
doaj   +3 more sources

FORMING THE ASSEMBLY AS A LEGISLATIVE BODY IN ANCIENT GREECE

open access: yesAnali Pravnog Fakulteta u Beogradu
In every democratic society, the role of the assembly is of utmost importance, as it is a political body whose main task is to represent the will of the people.
Vojislav STANIMIROVIĆ, Una Divac
doaj   +1 more source

The constitutional rationalization of the separation of powers: The case of Serbia [PDF]

open access: yesZbornik Radova Pravnog Fakulteta u Nišu, 2019
The main goal of this paper is to analyze the modalities of the separation of powers in the constitutional state. The starting point is that "pure" forms of separation of powers no longer exist even in traditional constitutional states, whereas in the so-
Pejić Irena
doaj  

Author Correction: Longitudinal unzipping of 2D transition metal dichalcogenides

open access: yesNature Communications, 2020
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Suchithra Padmajan Sasikala   +6 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

The Codification of the Law of Conflict of Interest (incompatibilitas) in Hungary in the 19th Century

open access: yesJournal on European History of Law, 2011
I intend to present in my paper the development of codification of conflict of interest, which is still a very important legal institution of Hungarian parliamentary system.
Norbert Varga
doaj   +2 more sources

The Establishment of North-Eastern Borders of Romania: International and Legal Support for Incorporation of the Bessarabia Lands into the Kingdom (end of 1919 — the 1st half of 1920)

open access: yesКиївські історичні студії
The foreign policy of Romania throughout the first decades of the 20th century was neither unplanned nor spontaneous. It was pursued by the Kingdom’s leadership within the framework of the idea of establishing the “Greater Romania”. Generally, the policy
Yaroslav Popenko   +3 more
doaj   +1 more source

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