Results 211 to 220 of about 2,559,156 (307)
Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang +10 more
wiley +1 more source
Injury Patterns and Physiologic Risk Stratification in Facial Trauma Patients with Orbital Fractures: A National Trauma Database Analysis. [PDF]
Mahfoz TB.
europepmc +1 more source
Low‐affinity antibodies are frequently disregarded in discovery pipelines. This work reports P5‐1C8, a Class 1 SARS‐CoV‐2 antibody with weak trimer binding (KD‐to‐IC50 > 3700‐fold) yet potent neutralization of Omicron JN.1. Structural, biophysical, functional, and coarse‐grained simulations collectively demonstrate that transient inter‐spike IgG ...
Niannian Lv +29 more
wiley +1 more source
Shifting power dynamics in global health governance: a challenge and an opportunity for Asia and the Global South. [PDF]
Rao NV +9 more
europepmc +1 more source
A schematic diagram of the mechanism where small extracellular vesicles mediate the enhancement of heterotopic wound healing by radial extracorporeal shockwave stimulation at a proximal tibial osteotomy site. ABSTRACT Wound healing represents a complex biological process necessitating innovative therapeutic approaches, particularly for chronic wounds ...
Xiaoping Xie +8 more
wiley +1 more source
Occupational Health Hazards and Morbidities among Bank Employees in a Metropolitan City, with Special Reference to Hypertension. [PDF]
Hadaye RS, Varughese CS.
europepmc +1 more source
Cryo‐EM analysis reveals an asymmetric MMOH–MMOB complex with distinct protomers, where MMOB binding triggers structural rearrangements from the surface to the active site. This conformational asymmetry shortens the Fe···Fe distance to 2.7 Å in one protomer, forming a geometry suitable for O2 activation and supporting a sequential catalytic mechanism ...
Yunha Hwang +9 more
wiley +1 more source
Test-Time Augmentations and Quality Controls for Improving Regional Seismic Phase Picking. [PDF]
Han B, Tang L, Ma L, Kong H, Xiao Z.
europepmc +1 more source
All‐hydrogel based n‐type depletion‐mode OECTs is developed using a semiconductor hydrogel formed via ionic‐liquid‐mediated phase separation, combining efficient ion‐electron transport, tissue‐like softness, and long‐term biocompatibility. The device can monitor EOG and ECG on human skin and record real‐time ECG subcutaneously in rats, providing a ...
Qicheng Liang +14 more
wiley +1 more source

