CONSUMER PREFERENCES FOR NATIONAL VS. GENERIC BRANDS IN BLIND TASTE AND TOUCH TEST
, 1983 Daniel J. McLaughlin +1 more
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
TREX1, a predator for treating MSI‐H tumors?
Molecular Oncology, EarlyView.Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya +2 more
wiley +1 more source
Tobacco Use InsightsBackground Electronic cigarettes (e-cigarettes) remain the most used tobacco product among young people in the United States (US). Given the need for current data on popular e-cigarette products, the current study leverages data from a rapid surveillance
Elizabeth K. Do +4 more
doaj +1 more source
Is a cigarette brand with fewer chemicals safer? Public perceptions in two national US experiments
, 2022 Michael Byron +2 more
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Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Progress, Liberty and National Identity, or Outdatedness, Aristocratic Snobbery and Helpless Liberalism – Intellectual Attitudes Towards Georg Brandes in Hungary between 1870 and 1914 [PDF]
, 2023 Anita Soós, Gábor Attila Csúr
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ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Understanding national brand customer erosion: exploring socio-demographic and weight of purchase factors [PDF]
José Miguel Holgado-Herrero +3 more
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The Nature and Benefits of National Brand/Private Label Competition [PDF]
, 2004 Robert L. Steiner
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