Results 171 to 180 of about 370,662 (286)

115. All-trans retinoic acid drug development at the national cancer institute (NCI)

Biomedicine & Pharmacotherapy, 1992
DR Parkinson, HC Stevenson, A Smith, BD Cheson, A Friedman   +4 more
openaire   +1 more source

Systemic anti‐cancer therapy associated with the occurrence of peripheral neurotoxicity and, specifically, peripheral neuropathy

International Journal of Cancer, EarlyView.
What's New? While the effectiveness of systemic anticancer therapy is well documented, it commonly causes severe toxicity. This study of the 467 systemic anticancer therapy agents currently approved globally for clinical and/or research purposes found that peripheral neurotoxicity is associated with 45% of classical chemotherapies, 21% of targeted ...
Cassie Higgins, Lynn R. Gauthier, Blair H. Smith, Lesley Colvin   +3 more
wiley   +1 more source

Ultrasound–triggered tumor‐selective nitric oxide release enhances tumor penetration of antibody–conjugated nanomedicine

Interdisciplinary Medicine, EarlyView.
Ultrasound‐triggered nitric oxide release from S‐nitrosated hyaluronic acid (HA‐SNO) induces tumor vasodilation and disrupts the vascular barrier, potently enhancing the intratumoral penetration of antibody‐conjugated nanomedicines. Abstract The tumor vascular barrier restricts the penetration of antibody‐conjugated nanomedicine, severely limiting its ...
Xiaodong Wang, Ruifeng Duan, Xin Chen, Tongjun Liu, Zhilin Liu   +4 more
wiley   +1 more source

Evaluation of Acute Exposure to Combustible and Novel Tobacco Products Using an In Vitro Human Airway Organ Tissue Equivalent Model

Journal of Applied Toxicology, EarlyView.
ABSTRACT Despite the well‐known risks of tobacco use, tobacco exposure remains a major contributor to morbidity and mortality worldwide. Although cigarette use has declined, the popularity of novel tobacco products (NTPs), such as electronic cigarettes (ECs) and heated tobacco products (HTPs), has increased.
Timothy S. Leach, Steven Albertson, Phillip W. Clapp, Vikram Surendran, Trang Simon, Eric C. Donny, Stephen J. Walker, Anthony Atala, Sean V. Murphy   +8 more
wiley   +1 more source

Clinical and demographic characteristics of adolescents, emerging adults, and young adults presenting to an emergency department following a suicide attempt

JCPP Advances, EarlyView.
Abstract Introduction Suicide is a significant public health concern and the second leading cause of death in adolescents and young adults. This study sought to better understand differences in demographic and clinical characteristics of young people who attempted suicide during three phases of this developmental period: late adolescence (14–17 years),
Nicholas M. Brdar, Natasha K. Matta, Chloe A. Miner, Mubashshir R. Bhuiyan, Irmgard G. Pallas, Anna L. Bickersteth, Hailey G. Prokop, Lindsay A. Bornheimer   +7 more
wiley   +1 more source

Towards Clinical Translation of Intravoxel Incoherent Motion MRI: Acquisition and Analysis Consensus Recommendations

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Intravoxel incoherent motion (IVIM) MRI allows for simultaneous assessment of tissue microcirculation (perfusion) and diffusion of water. In single‐center studies, IVIM has shown great potential for diagnosis, treatment outcome prediction, and treatment monitoring for many different diseases and organs.
Eric E. Sigmund, Susanne S. Rauh, Mami Iima, Christian Federau, Diego Hernando, Oscar Jalnefjord, Jacobus F. A. Jansen, Jonas Jasse, Neil Peter Jerome, Misha P. T. Kaandorp, Sila Kurugol, Frederik B. Laun, Mira M. Liu, Alexandra Ljimani, Thoralf Niendorf, David A. Reiter, Mohammed Salman Shazeeb, Amita Shukla‐Dave, Julia Stabinska, Andreas Wetscherek, Peter T. While, Dan Wu, Denis Le Bihan, Oliver J. Gurney‐Champion   +23 more
wiley   +1 more source

A novel analysis methodology for assessment of re-identification risks for the National Cancer Institute cancer registry privacy preserving record linkage technique. [PDF]

J Am Med Inform Assoc
Kantarcioglu M, Howe W, Liu B, Petkov V, Casas-Silva E, Velasquez-Kolnik D, Malin BA, Penberthy L.   +7 more
europepmc   +1 more source

Return to baseline arsenic concentrations after 1 year on gluten‐free diet in children with celiac disease: A prospective cohort study

JPGN Reports, EarlyView.
Abstract Objectives Lifelong adherence to a gluten‐free diet (GFD) is the primary treatment for celiac disease (CeD). Concerns have been raised about increased exposure to contaminants in a GFD because rice, which naturally bioaccumulates arsenic and other environmental contaminants, is commonly used as a substitute for gluten.
Nan Du, Clara Baek, Rachel Rosen, Tracy Punshon, Jocelyn A. Silvester   +4 more
wiley   +1 more source

NCI-Designated Cancer Centers' Policies and Practices with regard to Alcohol and Cancer: A Call to Lead. [PDF]

Cancer Epidemiol Biomarkers Prev
Hawk ET, Martch SL, Si M, Shete S.
europepmc   +1 more source

Recurrent Maxillary Ameloblastoma Presenting as an External Auditory Canal Mass

The Laryngoscope, EarlyView.
Ameloblastoma with temporal bone involvement is exceedingly rare, with no prior reports of external auditory canal presentation. This case report demonstrates successful multidisciplinary management with extensive skull base resection and adjuvant radiation therapy, emphasizing the role of proton therapy in achieving tissue‐sparing treatment and long ...
Bailey H. Duhon, Adel K. El‐Naggar, Jeffrey N. Myers, William H. Morrison, Franco DeMonte, Paul W. Gidley   +5 more
wiley   +1 more source