Results 191 to 200 of about 370,662 (286)

Quantitative Imaging of Pyruvate Metabolism in a Patient With Anaplastic Thyroid Cancer

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Magnetic resonance imaging using hyperpolarized (HP) [1‐13C]‐pyruvate enables assessment of pyruvate metabolism in vivo and offers new insight into metabolic changes in response to cancer therapy. Widely used semi‐quantitative metrics of pyruvate metabolism can be affected by physiological factors that are extrinsic to intracellular ...
James A. Bankson, Joshua S. Niedzielski, Collin J. Harlan, Yunyun Chen, Christopher M. Walker, Philip L. Lorenzi, Lin Tan, Vikas Kundra, Matthew E. Merritt, Mukundan Ragavan, Dawid Schellingerhout, Renjie He, Yao Ding, Sahana Datar, Qing Wang, Christine B. Peterson, Clifton D. Fuller, Vlad C. Sandulache, Stephen Y. Lai   +18 more
wiley   +1 more source

Retraction Note: Predicting cancer prognosis and drug response from the tumor microbiome

Nature Communications
Leandro C. Hermida, E. Michael Gertz, Eytan Ruppin   +2 more
doaj   +1 more source

Phase II Study of Dabrafenib and Trametinib in Patients With Tumors With <i>BRAF</i>^<i>V600E</i> Mutations: Updated Results From NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocol H. [PDF]

JCO Precis Oncol
Salama AKS, Wang V, Macrae ER, Park JI, Chen HX, Gray RJ, McShane LM, Rubinstein LV, Patton D, Williams PM, Hamilton SR, Armstrong DK, Tricoli JV, Conley BA, Arteaga CL, Harris LN, O'Dwyer PJ, Chen AP, Flaherty KT.   +18 more
europepmc   +1 more source

Adipose Tissue‐Derived Small Extracellular Vesicles in Plasma Reveal Molecular Circuitries Underlying Glucose Intolerance

Obesity, EarlyView.
ABSTRACT Objective Glucose tolerance (GT) is a major effector for adipose tissue (AT) remodeling in obesity, yet its molecular mechanisms remain incompletely defined. We hypothesized that the biophysical and molecular profiles of AT‐derived small extracellular vesicles (sEVAT) change in response to glucose availability and differ by GT status.
Shalini Mishra, Yixin Su, Ashish Kumar, Sangeeta Singh, Brian S. Finlin, Fang‐Chi Hsu, Jingyun Lee, Cristina M. Furdui, Philip A. Kern, Swapan K. Das, Gagan Deep   +10 more
wiley   +1 more source

Exocyst complex regulates fungal-mediated IL-33 release from cancer cells. [PDF]

Signal Transduct Target Ther
Alam A, Mayengbam SS, Abrams SI, Qu J, Dey P.   +4 more
europepmc   +1 more source

Impact of Genetic Predisposition to Obesity on Long‐Term Maintenance of Modest Weight Loss in Postmenopausal Women

Obesity, EarlyView.
ABSTRACT Objective Long‐term weight regain limits the population‐level benefits of obesity interventions. We tested whether the polygenic risk score of BMI (PRSBMI) modifies weight trajectories following modest weight loss. Methods The analytic sample included 9897 postmenopausal women from the Women's Health Initiative Dietary Modification Trial (6132
Harold H. Lee, Christy L. Avery, Misa Graff, Daeeun Kim, Josh Arias, Linda Van Horn, Charles Kooperberg, Kari E. North   +7 more
wiley   +1 more source

Clinical and dosimetric dataset of time-to-event normal tissue complication probability for osteoradionecrosis. [PDF]

Sci Data
West NA, Kamel S, Wentzel A, Kaffey Z, Abdelaal M, Elisabeta Marai G, Canahuate G, Zhang X, Chen MM, Wahid KA, Rigert J, Brock KK, Chambers M, Otun AO, Aponte-Wesson R, He R, Naser MA, Hutcheson KA, Mohamed ASR, van Dijk LV, Moreno AC, Lai SY, Fuller CD, Humbert-Vidan L.   +23 more
europepmc   +1 more source

Rate of Hearing Loss in Platinum‐Naïve Patients Receiving Immune Checkpoint Inhibitors

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Hearing loss from immune checkpoint inhibitors (ICIs) has been documented in case reports and case series. We present the largest retrospective study investigating the rate of ICI‐related ototoxicity in a monitored cohort of platinum‐naïve patients. Study Design Retrospective cohort study. Setting Tertiary‐care center.
Kaitlyn A. Brooks, Christopher G. Gidley, Olivia Grimley, Catherine Wang, Shirin Jivani, Dianna Roberts, Aung Naing, Jack Phan, Katherine Hutcheson, Xin Wang, Paul W. Gidley, Marc‐Elie Nader   +11 more
wiley   +1 more source

GARDE-Chat: a scalable, open-source platform for building and deploying health chatbots. [PDF]

J Am Med Inform Assoc
Del Fiol G, Borsato E, Bradshaw RL, Bian J, Woodbury A, Gauchel C, Eilbeck KL, Maxwell W, Ellis K, Madeo AC, Schlechter C, Kukhareva PV, Allen CG, Kean M, Elkin EB, Sharaf R, Ahsan MD, Frey M, Davis-Rivera L, Kohlmann WK, Wetter DW, Kaphingst KA, Kawamoto K.   +22 more
europepmc   +1 more source