Results 121 to 130 of about 957,911 (238)

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

First Annual Report for Robot-Assisted Surgery Based on the National Clinical Database 2019 in Japan: Report on Three Major Gastrointestinal Fields. [PDF]

Asian J Endosc Surg
Takemasa I, Yamamoto H, Nishigori T, Fujita T, Makino T, Taniyama Y, Terashima M, Tokunaga M, Matsuyama T, Yamaguchi T, Iwata N, Katsuno H, Suda K, Kinugasa Y, Obama K, Kamei T, Uyama I, Watanabe M, Sakai Y, Kitagawa Y.   +19 more
europepmc   +1 more source

The impact of COVID-19 on surgical procedures in Japan: analysis of data from the National Clinical Database. [PDF]

Surg Today, 2022
Ikeda N, Yamamoto H, Taketomi A, Hibi T, Ono M, Niikura N, Sugitani I, Isozumi U, Miyata H, Nagano H, Unno M, Kitagawa Y, Mori M.   +12 more
europepmc   +1 more source

Challenges and Prospects of National Clinical Database

Iryo To Shakai, 2016
openaire   +2 more sources

Histopathological Evidence of Neurodegenerative Pathology in Epilepsy: A Systematic Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Epilepsy affects > 50 million people worldwide and is associated with a disproportionate burden of cognitive impairment. Emerging evidence suggests that neurodegenerative proteinopathies, particularly hyperphosphorylated tau (p‐tau) and amyloid‐β (Aβ), may contribute to cognitive dysfunction in people with epilepsy (PWE), even in the absence ...
Syeda Amrah Hashmi, Aleksander Luniewski, Vanessa Smith, Matthew McCord, Jaideep Kapur, Mark Quigg, Catherine Joshua, Ifrah Zawar   +7 more
wiley   +1 more source

Current status of neonatal surgery in Japan: An analysis of data from the National Clinical Database Pediatric Surgical Registry. [PDF]

Pediatr Surg Int
Masahata K, Tachimori H, Ishimaru T, Kawakubo N, Usui Y, Koike Y, Jimbo T, Nose S, Makita S, Honda S, Nakata M, Yoneda A, Ono S.   +12 more
europepmc   +1 more source

Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad, Pouya Metanat, Michael Thomas, Luke W. Bonham, Tyson Lam, Mehmet Kurt, Hong Nguyen, Tara Ellingson, Mauro Zucchelli, Stefano Casagranda, Quin Lu, Andreas M. Rauschecker, Leo Sugrue, Luis E. Savastano, Christopher P. Hess, Kamalini Ranasinghe, S. Andrew Josephson, Bruce L. Miller, Jennifer S. Yokoyama, Gil D. Rabinovici, Peter A. Ljubenkov, Lawren VandeVrede, Kambiz Nael   +22 more
wiley   +1 more source

Impact of Child-Pugh score on surgical outcomes after distal gastrectomy and right hemicolectomy: a retrospective study from the Japanese National Clinical Database. [PDF]

Int J Surg
Shimada A, Endo H, Itano O, Yamamoto H, Komatsu S, Hasegawa H, Kakeji Y, Shirabe K.   +7 more
europepmc   +1 more source

Analysis of risk factors for postoperative complications in non-small cell lung cancer: comparison with the Japanese National Clinical Database risk calculator. [PDF]

BMC Surg, 2022
Motono N, Ishikawa M, Iwai S, Yamagata A, Iijima Y, Uramoto H.   +5 more
europepmc   +1 more source

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source