Updated risk prediction model for pancreaticoduodenectomy using data from the National Clinical Database in Japan. [PDF]
Mizuma M +8 more
europepmc +1 more source
Region‐specific profiling of the gut microbiome is achieved non‐invasively using electronics‐free ingestible sampling capsules that activate at defined intestinal sites through stimuli‐responsive coatings. Deployed in a porcine dietary intervention model, the capsules resolve spatially distinct, fiber‐driven shifts in microbial composition and short ...
Devendra Sarnaik +8 more
wiley +1 more source
Survival of patients with squamous cell carcinoma of the breast compared with invasive ductal carcinoma by biological subtype: A matched analysis of the Japanese national clinical database-breast cancer registry. [PDF]
Ogita M +6 more
europepmc +1 more source
This review brings together 20 publications describing 11 robotic system families developed for instrument handling, sterile‐package opening, supply delivery, and operating room logistics. Perception is becoming more capable through deep learning and language‐guided control, but autonomy remains limited, evidence is largely laboratory‐based, and no ...
Eugenia Mawuenya Akpo +4 more
wiley +1 more source
International Comparison of Geriatric-Associated Variables in Major Gastroenterological Surgery Between National Clinical Database and American College of Surgeons National Surgical Quality Improvement Program. [PDF]
Kofunato Y +13 more
europepmc +1 more source
This study identified Danofloxacin as a novel supporter of the maintenance of mouse embryonic stem cell (ESC) pluripotency. It functions partially by inhibiting HDAC1, which increases specific histone acetylation marks and activates key genes like Tert and Prdm10.
Yan Zhang +8 more
wiley +1 more source
CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression
A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao +27 more
wiley +1 more source
Effects of the COVID-19 pandemic on surgical treatment for thoracic malignant tumor cases in Japan: a national clinical database analysis. [PDF]
Shintani Y +14 more
europepmc +1 more source
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin +20 more
wiley +1 more source
Nationwide Trends in Short-Term Outcomes After Low Anterior Resection for Rectal Cancer: A Pre- and Post-COVID-19 Analysis From the Japanese National Clinical Database, 2018-2023. [PDF]
Seishima R +13 more
europepmc +1 more source

