Results 61 to 70 of about 292,670 (296)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Nepremičninske evidence in novi koordinatni sistem v luči direktive INSPIRE : Real Estate Databases And The New Coordinate System In Relation To The Inspire Directive [PDF]

Geodetski Vestnik, 2010
V resoluciji št. 2 zadnjega simpozija EUREF, ki je bilmaja 2009 v Firencah, je poudarjen pomen direktiveINSPIRE, pri čemer se zlasti opozarja na pomenEvropskega terestričnega referenčnega sistema 1989(ETRS89) ter Evropskega vertikalnega ...
Sandi Berk, Mihaela Triglav Čekada, Blaž Barborič   +2 more
doaj  

Problem of coordination the use of national GNSS systems

, 2020
This paper put for discussion the idea of creation one consortium in charge to coordinate the use of national GNSS systems for the civil aviation, maritime and land traffic management. One should found the idea of creation the international commercial consortium on financial and economic facts.
Kapustin A., Zhukov G.
openaire   +1 more source

Unifying Commercial Laws of Nation States Coordination of Legal Systems and Economic Growth [PDF]

, 2011
This paper analyzes unifications of nationally defined commercial laws within an elementary non-cooperative game-theoretical framework. In the absence of any coordination, it is far from obvious that nation-states will ever succeed in selecting the very same commercial laws.
P. Jean-Jacques Herings, Arnald J. Kanning   +1 more
openaire   +2 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Kombinirani izračun EUREF GPS-kampanj na območju Slovenije : Combined Solution of the EUREF GPS Campaigns of the Territory of Slovenia [PDF]

Geodetski Vestnik, 2003
In order to establish a link between the Slovene coordinate system and the unified European coordinate system, three EUREF GPS campaigns with sites on the territory of Slovenia have been realized.
Marijan Marjanović, Žarko Komadina, Sandi Berk, Dalibor Radovan, Bojan Stopar   +4 more
doaj  

Associated factors to the perception of clinical coordination in the Catalan national health system [PDF]

European Journal of Public Health, 2019
Abstract Background Clinical coordination across levels of care is a priority for health systems. The aim is to analyse the factors associated to a high perception of clinical coordination of primary (PC) and secondary care (SC) doctors of the Catalan national health system (NHS).
M L Vázquez for GAIA, L Colomés, E Medarde, I Ramon, À Avecilla, P Plaja, F Cots, E Sánchez, I Vargas, L Esteve Matalí   +9 more
openaire   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source