Results 51 to 60 of about 26,701 (258)

Selective Modulation of OTUB1 Noncanonical Function via a bioPhosTAC Strategy

open access: yesAdvanced Science, EarlyView.
This work positions the versatile performance of the peptide‐based bioPhosTAC platform for dissecting phosphorylation‐dependent biology and expanding the scope of induced‐proximity technologies. We demonstrated that selective manipulation of a tyrosine phosphorylation site is sufficient to propagate coordinated cellular consequences.
Seung Un Seo   +7 more
wiley   +1 more source

Streptococcal Mannose Phosphotransferase System Component IID Is a Novel RANK‐Binding Osteoclastogenic Factor

open access: yesAdvanced Science, EarlyView.
Streptococcal mannose phosphotransferase system component IID (Man‐PTSIID) is identified as a novel RANK‐binding osteoclastogenic factor. By directly binding to RANK and activating NF‐κB independently of TLR2, Man‐PTSIID drives osteoclastogenesis and inflammatory bone destruction, uncovering an unexpected microbial mechanism underlying streptococcal ...
Chaeyeon Park   +13 more
wiley   +1 more source

Enforcement of EU Competition Rules in Estonia: Substantive Convergence and Procedural Divergence [PDF]

open access: yesYearbook of Antitrust and Regulatory Studies, 2014
A decade of decentralized enforcement of EU competition rules under the procedural framework of Regulation 1/2003 has produced a diverse enforcement record that varies among Member States.
Alexandr Svetlicinii
doaj  

Isosorbide‐Based Optically Clear Adhesives With Ultrahigh Transparency and Rapid Strain Recovery for Flexible Displays

open access: yesAdvanced Science, EarlyView.
Biomass‐derived isosorbide‐based PUDA crosslinker enables optically clear adhesives with ultrahigh transparency (99.8%), rapid strain recovery, and stable adhesion for flexible displays. ABSTRACT Flexible and foldable displays require optically clear adhesives (OCAs) that combine ultrahigh optical transparency with mechanical resilience under repeated ...
Yoonji Choi   +8 more
wiley   +1 more source

Space Jam‐Ming: Generating Interstitial Space Using Fragmented Granular GelMA to Investigate Novel Paradigms of Cancer Metastasis

open access: yesAdvanced Science, EarlyView.
Microgels enable independent control of stiffness and interstitial space, overcoming limitations of conventional 3D hydrogels. Using fragmented gelatin methacryloyl microgels, we show that stiffness does not restrict non‐metastatic breast cancer growth, contrary to bulk hydrogels, and reveal the role of adherent‐to‐suspension transition in cancer ...
Danielle Vahala   +15 more
wiley   +1 more source

Long‐Term Human Skin Platform for Modeling Chronic Inflammation, Environmental Stress, and Therapeutic Intervention

open access: yesAdvanced Science, EarlyView.
An advanced, long‐term human skin platform maintains native skin structure and key tissue functions for up to four weeks. The platform models chronic inflammation, aging‐related skin changes, and UVB damage, enabling drug and topical interventions—including anti‐inflammatory therapy, senolytic treatment, and sunscreen—to be evaluated in intact human ...
Purnendu Kumar Sharma   +14 more
wiley   +1 more source

From Nuremberg to the Hague and beyond: International criminal law in courts: Court of Bosnia And Herzegovina as an example

open access: yesBratislava Law Review, 2019
International criminal law in courts will seize our interest forever. Adjudication of international criminal law violations have to happen in and by courts. They may be national courts; they also may be international (permanent or ad hoc) courts.
Manfred Dauster
doaj   +1 more source

Sui rapporti tra Carte e Corti: nuovi sviluppi nella ricerca di un sistema rapido ed efficace di tutela dei diritti fondamentali

open access: yesEuropean Papers, 2020
(Series Information) European Papers - A Journal on Law and Integration, 2020 5(1), 493-522 | European Forum Insight of 19 June 2020 | (Table of Contents) I. Introduzione: il quadro è chiaro... ma non troppo. - II.
Andrea Mastroianni
doaj   +1 more source

Excitation‐Selective Hydrochromic Upconversion in Zero‐Dimensional Metal Halides

open access: yesAdvanced Science, EarlyView.
Excitation wavelength dictates whether moisture speaks. In zero‐dimensional metal halides, the same humidity leaves the upconversion emission unchanged under 980 nm excitation yet triggers a distinct green‐to‐red shift under 1550 nm. This excitation‐selective hydrochromism, governed by the absorption at each wavelength, enables stimulus‐dependent ...
Joo Hyeong Han   +6 more
wiley   +1 more source

Authority of Judicial Decisions by the European Court of Justice in internal legal order

open access: yesZbornik Radova Pravnog Fakulteta u Splitu, 2014
European Court Judicial decisions are binding for all national courts, including the highest courts such as the Constitutional and the High Court. This applies to court practice in its entirety regardless of which member state is concerned.
Charlotte Denizeau
doaj  

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