Results 131 to 140 of about 5,004,752 (309)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Influence of national culture on mentoring relationship: a qualitative study of Japanese physician-scientists. [PDF]
BMC Med Educ, 2021 Obara H +4 more
europepmc +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
National culture and the organization's management are interdependent systems of values, which generate human performances that can reach levels of excellence.
Mihut Ioan
core
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Toward the understanding of national culture in the success of non-pharmaceutical technological interventions in mitigating COVID-19 pandemic. [PDF]
Ann Oper Res, 2022 Gupta M, Shoja A, Mikalef P.
europepmc +1 more source
Consuming identity : the case of Scotland [PDF]
, 2001 The paper examines national identity in Scotland. The research explores how consumers perceive the symbols used to represent Scotland, how these symbols relate to their perceptions of contemporary Scottish identity and their responses to the use of these
Coombes, Emma +3 more
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
The impact of national culture on the increase of COVID-19: A cross-country analysis of European countries. [PDF]
Int J Intercult Relat, 2021 Gokmen Y, Baskici C, Ercil Y.
europepmc +1 more source
, 2016 Carmichael shares his experiences of portraying Corporal Bobby Fields at Appomattox Court House National Historical Park in the summer of 1985. He uses Fields as a conduit to explore the scholarship pertaining to the common soldier of the Civil War and ...
Carmichael, Peter S.
core +1 more source