Results 131 to 140 of about 5,017,508 (309)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Investigating the cultural patterns of corruption: A nonparametric analysis [PDF]

open access: yes
By using a sample of 77 countries our analysis applies several nonparametric techniques in order to reveal the link between national culture and corruption.
Halkos, George, Tzeremes, Nickolaos
core   +1 more source

The impact of national culture on e-government implementation: A comparison case study [PDF]

open access: yes, 2009
Over the past decade there has been increasing interest in the IS research literature on the impact of cultural differences on the development and use of information and communications technologies (Ives & Jarvenpaa, 1991; Shore & Venkatachalam, 1995 ...
Ali, M, El-Haddadeh, R, Weerakkody, V
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

open access: yesFEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng   +2 more
wiley   +1 more source

Are National and Organizational Cultures Isomorphic? Evidence from a Four Country Comparative Study [PDF]

open access: yes
This pilot study investigates whether organizational practices as observed through differing organizational cultures systematically replicate or reject national values.
Rune Ellemose Gulev
core  

Changing Practice in a National Legal Deposit Library [PDF]

open access: yes, 2006
This two-part essay considers how digital culture has influenced ideas about permanence and looks at the change in collecting practice in a legal deposit library.
Mason, Ingrid
core  

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