Results 81 to 90 of about 27,553,759 (265)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Battle flags hanging in Ohio History Center plaza
, 1970 Photograph of Ohio's Battle Flag collection hanging in the plaza of the Ohio History Center in Columbus, Ohio, ca. 1970. The flags were displayed on the Center’s plaza level from the time the building opened in 1970 through the late 1980s, when they were
Ohio History Connection
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Вестник Мининского университета, 2017 The article is devoted to peculiarities of methodological approaches to study of applied art works of historicism epoch on the collection of the Radishchev Art Museum in Saratov.
T. E. Savitskaya
doaj +2 more sources
Excerpt, Oral History Interview, Frank A. Kasama
, 1980 Excerpt, summary, and index of an oral history interview of Frank A. Kasama. Conducted by Eric Saul on April 9, 1980, in San Francisco, CA. Transcribed by Malia Ema Okamura.This oral history interview was conducted for the MIS Oral History Project by the
Frank A. Kasama, Eric Saul
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FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Reflexões periféricas sobre a difusão internacional do pensamento econômico
Nova Economia, 2009 This article discusses the broad topic of the international diffusion of economic ideas and theories, by stressing its relevance for a better understanding of the process of formation of economic thought on a national scale.
José Luís Cardoso
doaj
Excerpt, Oral History Interview, Atusko Moriuchi
, 1986 Excerpt, summary, and index of an oral history interview of Atusko Moriuchi. Conducted by Eric Saul on August 2, 1986, in San Francisco, CA. Transcribed by Yi-Shen Loo.This oral history interview was conducted for the MIS Oral History Project by the ...
Atsuko Moriuchi, Eric Saul
core
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source