Results 211 to 220 of about 145,773 (300)

Anti‐Carbamylated Protein Antibodies Stabilize Carbamylated Histone H3 to Promote Synovial Activation and Neutrophil Extracellular Trap‐Mediated Bone Loss in Rheumatoid Arthritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Carbamylation, a nonenzymatic post‐translational modification, contributes to rheumatoid arthritis (RA) pathogenesis. Anti‐carbamylated protein antibodies (anti‐CarP) occur in around 50% of patients with RA and associate with greater joint damage. Neutrophil extracellular traps (NETs) are a major source of carbamylated autoantigens. We sought
Shuichiro Nakabo   +9 more
wiley   +1 more source

Autoantibodies to Joint‐Related Peptides Are Associated with Onset of Rheumatoid Arthritis in Presymptomatic Seronegative Individuals

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To identify autoantibodies in presymptomatic individuals that associate with the onset of rheumatoid arthritis (RA), and to distinguish early RA from osteoarthritis (OA), particularly in individuals lacking classic RA serological markers. Methods We analyzed serum and plasma from three cohorts: pre‐symptomatic individuals who later developed ...
Outi Sareila   +12 more
wiley   +1 more source

Modeling and parameter estimation for fractional large‐scale interconnected Hammerstein systems

open access: yesAsian Journal of Control, EarlyView.
Abstract This paper addresses the challenge of modeling and identifying large‐scale interconnected systems exhibiting memory effects, hereditary properties, and non‐local interactions. We propose a fractional‐order extension of the Hammerstein architecture that incorporates Grünwald–Letnikov operators to capture complex dynamics through multiple ...
Mourad Elloumi   +2 more
wiley   +1 more source

Parenting Stress and Stressful Life Events Among Caregivers of Toddler Siblings of Autistic and Non‐Autistic Children

open access: yesAutism Research, EarlyView.
ABSTRACT This study measured experiences of parenting stress and stressful life events in caregivers of families with a toddler who has either an autistic or non‐autistic older sibling(s). Caregivers of toddlers (12–18 months old) with older autistic siblings (Sibs‐autism; n = 58) and toddlers with older non‐autistic siblings (Sibs‐NA; n = 46 ...
Jennifer E. Magnuson   +9 more
wiley   +1 more source

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