Results 141 to 150 of about 20,884,318 (295)
Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni +9 morewiley +1 more sourceEpigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun +9 morewiley +1 more sourceNational identity predicts public health support during a global pandemic. [PDF]
Nat Commun, 2022 Van Bavel JJ, Cichocka A, Capraro V, Sjåstad H, Nezlek JB, Pavlović T, Alfano M, Gelfand MJ, Azevedo F, Birtel MD, Cislak A, Lockwood PL, Ross RM, Abts K, Agadullina E, Aruta JJB, Besharati SN, Bor A, Choma BL, Crabtree CD, Cunningham WA, De K, Ejaz W, Elbaek CT, Findor A, Flichtentrei D, Franc R, Gjoneska B, Gruber J, Gualda E, Horiuchi Y, Huynh TLD, Ibanez A, Imran MA, Israelashvili J, Jasko K, Kantorowicz J, Kantorowicz-Reznichenko E, Krouwel A, Laakasuo M, Lamm C, Leygue C, Lin MJ, Mansoor MS, Marie A, Mayiwar L, Mazepus H, McHugh C, Minda JP, Mitkidis P, Olsson A, Otterbring T, Packer DJ, Perry A, Petersen MB, Puthillam A, Riaño-Moreno JC, Rothmund T, Santamaría-García H, Schmid PC, Stoyanov D, Tewari S, Todosijević B, Tsakiris M, Tung HH, Umbreș RG, Vanags E, Vlasceanu M, Vonasch A, Yucel M, Zhang Y, Abad M, Adler E, Akrawi N, Mdarhri HA, Amara H, Amodio DM, Antazo BG, Apps M, Ay FC, Ba MH, Barbosa S, Bastian B, Berg A, Bernal-Zárate MP, Bernstein M, Białek M, Bilancini E, Bogatyreva N, Boncinelli L, Booth JE, Borau S, Buchel O, Cameron CD, Carvalho CF, Celadin T, Cerami C, Chalise HN, Cheng X, Cian L, Cockcroft K, Conway J, Córdoba-Delgado MA, Crespi C, Crouzevialle M, Cutler J, Cypryańska M, Dabrowska J, Daniels MA, Davis VH, Dayley PN, Delouvee S, Denkovski O, Dezecache G, Dhaliwal NA, Diato AB, Di Paolo R, Drosinou M, Dulleck U, Ekmanis J, Ertan AS, Etienne TW, Farhana HH, Farkhari F, Farmer H, Fenwick A, Fidanovski K, Flew T, Fraser S, Frempong RB, Fugelsang JA, Gale J, Garcia-Navarro EB, Garladinne P, Ghajjou O, Gkinopoulos T, Gray K, Griffin SM, Gronfeldt B, Gümren M, Gurung RL, Halperin E, Harris E, Herzon V, Hruška M, Huang G, Hudecek MFC, Isler O, Jangard S, Jørgensen FJ, Kachanoff F, Kahn J, Dangol AK, Keudel O, Koppel L, Koverola M, Kubin E, Kunnari A, Kutiyski Y, Laguna O, Leota J, Lermer E, Levy J, Levy N, Li C, Long EU, Longoni C, Maglić M, McCashin D, Metcalf AL, Mikloušić I, El Mimouni S, Miura A, Molina-Paredes J, Monroy-Fonseca C, Morales-Marente E, Moreau D, Muda R, Myer A, Nash K, Nesh-Nash T, Nitschke JP, Nurse MS, Ohtsubo Y, Oldemburgo de Mello V, O'Madagain C, Onderco M, Palacios-Galvez MS, Palomäki J, Pan Y, Papp Z, Pärnamets P, Paruzel-Czachura M, Pavlović Z, Payán-Gómez C, Perander S, Pitman MM, Prasad R, Pyrkosz-Pacyna J, Rathje S, Raza A, Rêgo GG, Rhee K, Robertson CE, Rodríguez-Pascual I, Saikkonen T, Salvador-Ginez O, Sampaio WM, Santi GC, Santiago-Tovar N, Savage D, Scheffer JA, Schönegger P, Schultner DT, Schutte EM, Scott A, Sharma M, Sharma P, Skali A, Stadelmann D, Stafford CA, Stanojević D, Stefaniak A, Sternisko A, Stoica A, Stoyanova KK, Strickland B, Sundvall J, Thomas JP, Tinghög G, Torgler B, Traast IJ, Tucciarelli R, Tyrala M, Ungson ND, Uysal MS, Van Lange PAM, van Prooijen JW, van Rooy D, Västfjäll D, Verkoeijen P, Vieira JB, von Sikorski C, Walker AC, Watermeyer J, Wetter E, Whillans A, Willardt R, Wohl MJA, Wójcik AD, Wu K, Yamada Y, Yilmaz O, Yogeeswaran K, Ziemer CT, Zwaan RA, Boggio PS. +256 moreeuropepmc +1 more sourceTranslating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD) Sejung Lee, Junghyeok Lim, Jinhyuk Bhinwiley +1 more source