Results 61 to 70 of about 24,111,558 (299)
District plan implementation under the RMA: Confessions of a resource consent [PDF]
, 2003 This report focuses on results from Phase 2 of PUCM - the quality of plan implementation in six district councils selected for their range of plan quality and capacity to plan.
Barfoot, Cushla +13 more
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FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
The cost of implementing Vietnam’s national plan of action for nutrition for 2017–2020
AIMS Public Health, 2019 Existe una necesidad urgente de llevar a cabo un ejercicio de costeo del Plan Nacional de Acción para la Nutrición (NPAN) 2017-2020, ya que el costeo de las intervenciones sensibles a la nutrición no estaba completamente integrado y resultó difícil realizar un seguimiento de las contribuciones de los diferentes sectores al programa de nutrición.
Hoàng Văn Minh +9 more
openaire +3 more sources
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
National Action Plan for Energy Efficiency, Chapter 6: Energy Efficiency Program Best Practices
, 2006 Chapter from the National Action Plan for Energy Efficiency documenting key findings from energy efficiency programs that have been successfully operating for many ...
National Action Plan for Energy Efficiency (U.S.)
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Connecting for Life Implementation Plan 2023-2024
, 2023 The 2023-2024 implementation plan for Connecting for Life, Ireland's National Strategy to Reduce ...
HSE National Office for Suicide Prevention (NOSP)
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Designing a model for implementing diagnosis‐related groups in Iran: An action plan approach
Health Science ReportsBackground and Aims Implementing diagnosis‐related groups (DRGs) in different countries increases the efficiency of healthcare services, improves treatment quality, and reduces treatment costs.
Farkhondeh Asadi +3 more
doaj +1 more source