The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort
Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo +9 more
wiley +1 more source
Innovation System Policies in Less Successful Developing countries: The case of Thailand [PDF]
The issue of the rationale for public intervention under the systems of innovation perspective has recently received an increasing attention among scholars and practitioners. However, with few exceptions, this literature has been based on the analysis of
Intrakumnerdi, Patarapong +1 more
core
Spatiotemporal evolution of innovation collaboration networks in China's AI medical device industry: implications for public health governance. [PDF]
Hu F +9 more
europepmc +1 more source
Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns
Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki +6 more
wiley +1 more source
Low-Concentration Enhancement Effect: Enabling Sensitive Detection of EML4-ALK Variants via Multiplex RT-MIRA. [PDF]
Ren XD +10 more
europepmc +1 more source
Frailty Predicts Incident Osteoporotic Fractures in Veterans with Rheumatoid Arthritis
Objective Rheumatoid arthritis (RA) is associated with an increased risk of frailty and osteoporosis, but the relationship between frailty and incident osteoporotic fractures in RA is underexplored. Methods Data were from the Veterans Affairs (VA) Rheumatoid Arthritis Registry. Frailty was measured using the VA Frailty Index (VAFI).
Katherine D. Wysham +14 more
wiley +1 more source
Understanding innovation system build up: The rise and fall of the Dutch PV Innovation System [PDF]
Renewable energy technologies have a hard time to break through in the existing energy regime. In this paper we focus on analysing the mechanisms behind this problematic technology diffusion.
Wilfried van Sark +3 more
core
Engaging tuberculosis-affected people in investment decisions: applying a people-centered design approach in Viet Nam. [PDF]
Forse R +25 more
europepmc +1 more source
Development of a Disease Activity Index for the Assessment of VEXAS Syndrome (VEXAS‐DAI)
Objective Vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic syndrome (VEXAS) syndrome is characterized by a complex spectrum of inflammatory and hematologic manifestations. Clinical research to identify effective therapies is urgently needed but is hindered by the lack of validated outcome measures.
Kevin Byram +25 more
wiley +1 more source
A Multi-Partner Effort to Launch and Sustain Wastewater Surveillance, United States. [PDF]
Yoder J +15 more
europepmc +1 more source

