Results 121 to 130 of about 999,131 (304)

Staphylococcus epidermidis—key to understanding biofilms, commensalism, and more

Journal of Bacteriology
Staphylococcus epidermidis, a ubiquitous inhabitant of human skin, has been known for decades for its capacity to form biofilm-associated infections on indwelling medical devices and has developed into a leading bacterium used in biofilm research.
Gordon Y. C. Cheung, Michael Otto
doaj   +1 more source

European study of research and development in mobility technology for persons with disabilities

Journal of NeuroEngineering and Rehabilitation, 2012
In the fall of 2010, the National Science Foundation, the National Institutes of Health and the U.S. Veteran's Administration jointly supported a review of mobility technology in Europe.
Caufield Brian, Conway Ted A, Micera Silvestro   +2 more
doaj   +1 more source

Loss of cardiac microRNA-mediated regulation leads to dilated cardiomyopathy and heart failure [PDF]

, 2009
Rationale: Heart failure is a deadly and devastating disease that places immense costs on an aging society. To develop therapies aimed at rescuing the failing heart, it is important to understand the molecular mechanisms underlying cardiomyocyte ...
Bauer, Michael, Blelloch, Robert, Chiang, H. Rosaria, Gupta, Sumeet, Jaenisch, Rudolf, Krieger, Monty, Liao, Ronglih, Lodish, Harvey F., Medvid, Rostislav, Rao, Prakash K., Reinhardt, Ferenc, Toyama, Yumiko   +11 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Sharing clinical research data in the United States under the health insurance portability and accountability act and the privacy rule

Trials, 2010
Sharing of final research data from clinical research is an essential part of the scientific method. The U.S. National Institutes of Health require some grant applications to include plans for sharing final research data, which it defines as the factual ...
Miller James D
doaj   +1 more source

InVERT molding for scalable control of tissue microarchitecture [PDF]

, 2012
Complex tissues contain multiple cell types that are hierarchically organized within morphologically and functionally distinct compartments. Construction of engineered tissues with optimized tissue architecture has been limited by tissue fabrication ...
A Atala, AA Chen, AG Mikos, AM Kloxin, BS Ding, BS Ding, CA DeForest, CM Brophy, CM Nelson, CM Williams, DR Albrecht, EE Hui, GH Underhill, H Hamada, H Tekin, JC Culver, JS Miller, JW Franses, K Jakab, K Matsumoto, K Si-Tayeb, KR Stevens, MD Ungrin, O Cleaver, P Muller, P Muller, R Gaebel, R Glicklis, RE Schwartz, RG Wylie, S Levenberg, S MacNeil, S Raghavan, SF Abu-Absi, SF Wong, SN Bhatia, SR Khetani, SR Khetani, SR Khetani, V Liu Tsang, V Mironov, Y Nahmias   +41 more
core   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Correction to: Introduction to collection: confronting the challenges of health research in humanitarian crises

Conflict and Health, 2021
Amit S. Mistry, Brandon A. Kohrt, Blythe Beecroft, Nalini Anand, Iman Nuwayhid   +4 more
doaj   +1 more source

Cognitive Information Processing [PDF]

, 1969
Contains reports on seven research projects.National Institutes of Health (Grant 5 P01 GM14940-03)National Institutes of Health (Grant 5 P01 GM15006-02)Joint Services Electronics Programs (U. S. Army, U.S. Navy, and U.S.
Allen, J. L., Anderson, G. B., Barnwell, T. P., III, Bowie, J. E., Lee, W-H., Robbins, G. M., Woods, J. W.   +6 more
core