Results 131 to 140 of about 964,883 (379)

Exploring Food, Agricultural, and Environmental Law and Policy Reforms

Journal of Agriculture, Food Systems, and Community Development, 2016
First paragraphs: Books have played an important role in shaping the United States' food, agricultural, and environmental systems. One of the most influential is a1906 book entitled The Jungle written by Upton Sinclair that used investigative reporting ...
Sheila Fleischhacker
doaj  

European study of research and development in mobility technology for persons with disabilities

Journal of NeuroEngineering and Rehabilitation, 2012
In the fall of 2010, the National Science Foundation, the National Institutes of Health and the U.S. Veteran's Administration jointly supported a review of mobility technology in Europe.
Caufield Brian, Conway Ted A, Micera Silvestro   +2 more
doaj   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

Correction of rotational distortion for catheter-based en face OCT and OCT angiography [PDF]

, 2014
We demonstrate a computationally efficient method for correcting the nonuniform rotational distortion (NURD) in catheter-based imaging systems to improve endoscopic en face optical coherence tomography (OCT) and OCT angiography.
Ahsen, Osman Oguz, Fujimoto, James G., Giacomelli, Michael Gene, Lee, Hsiang-Chieh, Liang, Kaicheng, Mashimo, Hiroshi, Potsaid, Benjamin M., Tsai, Tsung-Han, Wang, Zhao   +8 more
core   +1 more source

FEDERAL SUPPORT OF SCIENTIFIC INQUIRY IN THE UNITED STATES: CURRENT EVOLUTION UNDER THE POLITICAL STRUGGLE

Сравнительная политика, 2016
2000’s and 2010’s witnessed diminishing margin of the United States in science and technology. Meanwhile, the U.S. remains a clear leader in this fi eld. Major driving force of the country’s success in the second half of the ХХ century remained assertive
I. A. Istomin
doaj   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Degradable Terpolymers with Alkyl Side Chains Demonstrate Enhanced Gene Delivery Potency and Nanoparticle Stability [PDF]

, 2012
Degradable, cationic poly(β-amino ester)s (PBAEs) with alkyl side chains are developed for non-viral gene delivery. Nanoparticles formed from these PBAE terpolymers exhibit significantly enhanced DNA transfection potency and resistance to aggregation ...
Alabi, Christopher A., Anderson, Daniel Griffith, Chen, Delai, Eltoukhy, Ahmed A., Langer, Robert S   +4 more
core   +1 more source

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

Molecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita, Varda Shoshan‐Barmatz   +1 more
wiley   +1 more source

Magic Angle Spinning Nuclear Magnetic Resonance Characterization of Voltage-Dependent Anion Channel Gating in Two-Dimensional Lipid Crystalline Bilayers [PDF]

, 2014
National Institutes of Health (U.S.) (EB001960)National Institutes of Health ...
Andreas, Loren, Clark, Lindsay, Eddy, Matthew Thomas, Griffin, Robert Guy, Noskov, Sergei Y., Rostovtseva, Tatiana K., Su, Yongchao, Teijido, Oscar, Wagner, Gerhard   +8 more
core   +1 more source

Faculty Attitudes toward Open Access and Scholarly Communications: Disciplinary Differences on an Urban and Health Science Campus

Journal of Librarianship and Scholarly Communication, 2017
Access to scholarship in the health sciences has greatly increased in the last decade. The adoption of the 2008 U.S. National Institutes of Health Public Access Policy and the launch of successful open access journals in health sciences have done much to
Emily Dill, Jere Odell, Kristi Palmer
doaj   +2 more sources