Results 211 to 220 of about 964,883 (379)

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source

Health and aging trajectories: shared and competing risks and resiliencies for chronic diseases associated with aging. A NIH-wide workshop. [PDF]

Front Public Health
Rovira II, Biragyn A, Brown LL, Galis ZS, Klauzinska M, Kotliarova SE, Simmons JM, Wali A, Xi D, Yarden RI, Riscuta G.   +10 more
europepmc   +1 more source

Changes in Scalp Hair Roots as a Measure of Toxicity from Cancer Chemotherapeutic Drugs**From the Dermatology Service, General Medicine Branch, National Cancer Institute, (National Institutes of Health, Public Health Service, U.S. Department of Health, Education and Welfare) Bethesda, Maryland.

, 1960
Robert G. Crounse, Eugene J. Van Scott
openalex   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

Securing Global Health in the Face of Changing U.S. Policy: The Case for Strengthening National Public Health Institutes

Quentin Sandifer, Duncan Selbie, Sadaf Lynes, Neil Squires   +3 more
openalex   +2 more sources

Lifespan reference curves for harmonizing multi-site regional brain white matter metrics from diffusion MRI. [PDF]

Sci Data
Zhu AH, Nir TM, Javid S, Villalón-Reina JE, Rodrigue AL, Strike LT, de Zubicaray GI, McMahon KL, Wright MJ, Medland SE, Blangero J, Glahn DC, Kochunov P, Williamson DE, Håberg AK, Thompson PM, Jahanshad N.   +16 more
europepmc   +1 more source

An Electron Microscopic Study of Human Epidermis**From the Division of Dermatology, (Dr. F. W. Lynch, Director); and the Department of Anatomy, University of Minnesota Medical School, Minneapolis, Minnesota.Aided by research grants M-388 and B-782 from the National Institute of Mental Health and the National Institute for Neurologic Diseases and Blindness, U.S. Public Health Service, and by the Graduate Medical Research Fund of the University of Minnesota.

, 1961
Alvin S. Zelickson, John F. Hartmann
openalex   +1 more source

National Institutes of Health Pathways to Prevention Workshop: The Role of Opioids in the Treatment of Chronic Pain

Annals of Internal Medicine, 2015
D. Reuben, A. Alvanzo, T. Ashikaga, G. Bogat, C. Callahan, V. Ruffing, D. Steffens   +6 more
semanticscholar   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

Sponsor's Foreword

The Scientific World Journal, 2007
David Shurtleff, Sergi Ferré
doaj   +1 more source