Results 51 to 60 of about 999,131 (304)

Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys [PDF]

, 2013
Human immunodeficiency virus type 1 (HIV-1)-specific monoclonal antibodies with extraordinary potency and breadth have recently been described. In humanized mice, combinations of monoclonal antibodies have been shown to suppress viraemia, but the ...
Barouch, Dan H., Beck, Matthew, Blackmore, Stephen, Borducchi, Erica N., Burton, Dennis R., Cabral, Crystal, Chakraborty, Arup K., Chang, Hui-Wen, Gupta, Sanjana, Klein, Florian, Lewis, Mark G., Liu, Jinyan, Moldt, Brian, Nkolola, Joseph P., Nussenzweig, Michel C., Oliveira, Thiago Y., Perry, James R., Poignard, Pascal, Rinaldi, William, Sanisetty, Srisowmya, Seaman, Michael S., Shekhar, Karthik, Smith, Jeffrey Y., Smith, Kaitlin M., Stephenson, Kathryn E., Whitney, James B.   +25 more
core   +6 more sources

Fifty Years of Supporting Global Health Research at the NIH Fogarty International Center

Annals of Global Health, 2019
For 50 years, the Fogarty International Center (FIC) has built research capacity particularly in low and middle-income countries responding to national and global public health priorities. Established in 1968 in honor of U.S. Congressman John E. Fogarty,
Kenneth Bridbord, Kristen H. Weymouth, Ann Puderbaugh, Celia Wolfman, Christopher W. Belter, Joel G. Breman, Peter H. Kilmarx   +6 more
doaj   +1 more source

Differential immunophenotype of circulating monocytes from pregnant women in response to viral ligands

BMC Pregnancy and Childbirth, 2023
Background Viral infections during pregnancy can have deleterious effects on mothers and their offspring. Monocytes participate in the maternal host defense against invading viruses; however, whether pregnancy alters monocyte responses is still under ...
Marcelo Farias-Jofre, Roberto Romero, Yi Xu, Dustyn Levenson, Li Tao, Tomi Kanninen, Jose Galaz, Marcia Arenas-Hernandez, Zhenjie Liu, Derek Miller, Gaurav Bhatti, Megan Seyerle, Adi L. Tarca, Nardhy Gomez-Lopez   +13 more
doaj   +1 more source

Effect of Intravitreous Anti–Vascular Endothelial Growth Factor Therapy on Choroidal Thickness in Neovascular Age-Related Macular Degeneration Using Spectral-Domain Optical Coherence Tomography [PDF]

, 2013
A critical method of monitoring patients with neovascular age-related macular degeneration (AMD) being treated with anti–vascular endothelial growth factor (anti-VEGF) is optical coherence tomography (OCT), which uses low-coherence interferometry of ...
Adhi, Mehreen, Branchini, Lauren, Duker, Jay S., Flores-Moreno, Ignacio, Fujimoto, James G., Manjunath, Varsha, Regatieri, Caio   +6 more
core   +1 more source

Potential Early Risk Biomarkers for Reduced Forced Expiratory Volume in Children Post‐Hematopoietic Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We sought to identify potential early risk biomarkers for lung disease in children post‐allogeneic HCT. Patients with pulmonary function tests 3 months post‐transplant and plasma samples between days 7 and 14 post‐HCT were included. Six of 27 subjects enrolled had reduced forced expiratory volume 1 (FEV1) z scores.
Isabella S. Small, Pi Chun Cheng, April L. Rahrig, Courtney M. Rowan   +3 more
wiley   +1 more source

Quantitative Susceptibility Mapping by Inversion of a Perturbation Field Model: Correlation With Brain Iron in Normal Aging [PDF]

, 2014
There is increasing evidence that iron deposition occurs in specific regions of the brain in normal aging and neurodegenerative disorders such as Parkinson's, Huntington's, and Alzheimer's disease.
Adalsteinsson, Elfar, Jenkinson, Mark, Pfefferbaum, Adolf, Poynton, Clare B., Sullivan, Edith V., Wells, William M.   +5 more
core   +1 more source

Personalizing the Pediatric Hematology/Oncology Fellowship: Adapting Training for the Next Generation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT The pediatric hematology‐oncology fellowship training curriculum has not substantially changed since its inception. The first year of training is clinically focused, and the second and third years are devoted to scholarship. However, this current structure leaves many fellows less competitive in the current job market, resulting in ...
Scott C. Borinstein, Melissa J. Rose, Scott Moerdler, Richard Ho   +3 more
wiley   +1 more source

Health Emergency Research Preparedness: An Analysis of National Pre‑COVID Research Activity and COVID Research Output

Annals of Global Health
Background: Research capacity is a critical element of health emergency preparedness, but metrics are not readily available for many countries. The COVID‑19 pandemic provided an opportunity to use publicly available data to assess correlations between ...
Peter H. Kilmarx, Shirley Kyere
doaj   +1 more source

Degradable Terpolymers with Alkyl Side Chains Demonstrate Enhanced Gene Delivery Potency and Nanoparticle Stability [PDF]

, 2012
Degradable, cationic poly(β-amino ester)s (PBAEs) with alkyl side chains are developed for non-viral gene delivery. Nanoparticles formed from these PBAE terpolymers exhibit significantly enhanced DNA transfection potency and resistance to aggregation ...
Alabi, Christopher A., Anderson, Daniel Griffith, Chen, Delai, Eltoukhy, Ahmed A., Langer, Robert S   +4 more
core   +1 more source

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source