Results 91 to 100 of about 8,906,651 (388)
The Irish Research electronic Library initiative – levelling the playing field? [PDF]
, 2008 Purpose - The Irish Research electronic Library (IReL) is a nationally funded electronic research library providing online access to full text articles from thousands of peer-reviewed publications in a range of disciplines.
Dunne, Siobhán
core +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Toxicological Sciences, 2018 To screen the tens of thousands of chemicals for which no toxicity data currently exists, it is necessary to move from in vivo rodent models to alternative models, such as zebrafish.
Katharina Dach +5 more
semanticscholar +1 more source
In Search of a New Model: Library Resource Sharing in China - A Comparative Study [PDF]
, 2007 This paper reviews the framework of library resource sharing (LRS) in China and examines, from a comparative perspective, cases of recent development, particularly in the 1990s and early 2000s. Highlights include: (1) historical review of LRS in the U.S.
Dong, Elaine Xiaofen, Zou, Tim Jiping
core +2 more sources
Legal Deposit Web Archives and the Digital Humanities: a Universe of Lost Opportunity? [PDF]
, 2018 Legal deposit libraries have archived the web for over a decade. Several nations, supported by legal deposit regu-lations, have introduced comprehensive national domain web crawling, an essential part of the national library re-mit to collect, preserve ...
Berube, Linda +2 more
core +3 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Digitisation and Digital Library Presentation System
Digital Humanities in the Nordic and Baltic Countries Publications, 2018 The National Library of Finland (NLF) has done long-term work to digitise and make available our unique collections. The digitisation policy defines what is to be digitised, and it aims not only to target both rare and unique materials but also to ...
Tuula Pääkkönen +2 more
doaj +1 more source
Lucy Salyer, Associate Professor of History, travels to England and Ireland [PDF]
, 2007 Professor Lucy Salyer traveled this summer to England and Ireland. While in England, she presented a paper at the Anglo-American Conference of Historians held in London and conducted research at the National Archives of the United Kingdom located in Kew.
Slayer, Lucy
core +2 more sources
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Introducing the National Library for Health Skin Conditions Specialist Library [PDF]
, 2005 Background: This paper introduces the new National Library for Health Skin Conditions Specialist Library http://www.library.nhs.uk/skin. Description: The aims, scope and audience of the new NLH Skin Conditions Specialist Library, and the composition ...
Grindlay, Douglas J.C. +2 more
core +2 more sources