Results 111 to 120 of about 3,341,945 (353)
This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li +10 more
wiley +1 more source
Objective RAId is a software package that has been actively developed for the past 10 years for computationally and visually analyzing MS/MS data. Founded on rigorous statistical methods, RAId’s core program computes accurate E-values for peptides and ...
Brendan Joyce +5 more
doaj +1 more source
Donald A.B. Lindberg and the U.S. National Library of Medicine transformed biomedical and health informatics. [PDF]
Miller RA, Shortliffe EH.
europepmc +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Don Lindberg's outreach legacy at the National Library of Medicine. [PDF]
Siegel ER.
europepmc +1 more source
Naked cuticle is essential for Drosophila wing development beyond Wingless signaling
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley +1 more source
Innovations of subject service in National Science Library, Chinese Academy of Sciences and the implications [PDF]
Looking at the development of subject librarians and subject services in Chinese libraries during the past decade, this paper highlights the innovative concepts and practices of subject librarians in National Science Library (NSL), Chinese Academy of ...
CHU Jingli +1 more
core
The multiple dimensions of expanded access to health information: Don Lindberg and the U.S. National Library of Medicine. [PDF]
Humphreys BL.
europepmc +1 more source

