Results 51 to 60 of about 6,074,244 (344)

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

Molecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld, Stefan Kühberger, Ricarda Graf, Christine Beichler, Markus Braun, Nadia Dandachi, Ellen Heitzer, Gerald W. Prager   +7 more
wiley   +1 more source

Correspondence of User Expectations with Staff Presumptions Regarding the Quality of Services Offered At [Iranian] National Library [PDF]

تحقیقات کتابداری و اطلاع‌رسانی دانشگاهی, 2011
Objective: The present investigation aims to determine the gap between users, understanding and expectation of services received with staff presumptions regarding their expectations.
N Neshat, mozhdeh dehghani
doaj  

Utilization of Information and Communication Technology in Coordination Between the National Library with the Provincial Library

Record and Library Journal, 2016
Changes are rapidly occur in this world, especially developments in the field of information and communication technology. Man must be able to adjust quickly to keep up.
Dimas A. Gammayani, Irham Hanif Nabawi, Muhammad Irsyad Alfatih   +2 more
doaj   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Spotlight on Special Libraries: The National Sporting Library and Museum

Virginia Libraries, 2012

National Sporting Library and Museum Staff
doaj  

Identification of entities in the Linked Data collection "Rainis and Aspazija" (RunA)

JLIS.it, 2018
This paper offers an insight into the work in progress — development of the Linked Data collection RunA http://runa.lnb.lv/ on two Latvian poets and opinion leaders (Rainis — Jānis Pliekšāns, 1865-1929 and Aspazija, Johanna Emīlija Lizete Rozenberga ...
Anita Goldberga, Maira Kreislere, Anita Rašmane, Aiva Stūrmane, Edgars Salna   +4 more
doaj   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Automatic Subject Cataloguing at the German National Library

Liber Quarterly: The Journal of European Research Libraries
The German National Library (DNB) began developing solutions for automatic subject cataloguing 15 years ago. The main reason for this was the huge and ever-growing number of digital media works that needed to be indexed.
Christoph Poley, Sandro Uhlmann, Frank Busse, Jan-Helge Jacobs, Maximilian Kähler, Matthias Nagelschmidt, Markus Schumacher   +6 more
doaj   +1 more source

VADR: validation and annotation of virus sequence submissions to GenBank

BMC Bioinformatics, 2020
Background GenBank contains over 3 million viral sequences. The National Center for Biotechnology Information (NCBI) previously made available a tool for validating and annotating influenza virus sequences that is used to check submissions to GenBank ...
Alejandro A. Schäffer, Eneida L. Hatcher, Linda Yankie, Lara Shonkwiler, J. Rodney Brister, Ilene Karsch-Mizrachi, Eric P. Nawrocki   +6 more
doaj   +1 more source