Results 61 to 70 of about 3,256,358 (354)

VADR: validation and annotation of virus sequence submissions to GenBank

open access: yesBMC Bioinformatics, 2020
Background GenBank contains over 3 million viral sequences. The National Center for Biotechnology Information (NCBI) previously made available a tool for validating and annotating influenza virus sequences that is used to check submissions to GenBank ...
Alejandro A. Schäffer   +6 more
doaj   +1 more source

Academic and special libraries in Croatia and their crisis preparedness: a survey

open access: yesLibellarium: Journal for the Research of Writing, Books, and Cultural Heritage Institutions, 2022
Purpose. This research aimed to assess the state of crisis preparedness, management, and the potentials of crisis response in academic and special libraries in Croatia.
Jelena Duh   +2 more
doaj   +1 more source

An International Prospectus for Library & Information Professionals: Development, Leadership and Resources for Evolving Patron Needs [PDF]

open access: yes, 2007
The roles of library and information professionals must change and evolve to: 1. accommodate needs of tech-savvy patrons; 2. thrive in the Commons & Library 2.0; 3. provide integrated, just-in-time services; 4. constantly update and enhance technology; 5.
Bailey, D. Russell
core   +1 more source

The Irish Research electronic Library initiative – levelling the playing field? [PDF]

open access: yes, 2008
Purpose - The Irish Research electronic Library (IReL) is a nationally funded electronic research library providing online access to full text articles from thousands of peer-reviewed publications in a range of disciplines.
Dunne, Siobhán
core   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

The Impact Of Federal Legislation On Governmental And Special Libraries [PDF]

open access: yes, 1966
It has become increasingly obvious that libraries today cannot provide adequate service under conditions of local self-sufficiency. A variety of programs are required on the national level which cannot be provided by individual libraries or ...
Skipper, James E.
core  

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu   +11 more
wiley   +1 more source

Setting up a National Research Data Curation Service for Qatar: Challenges and Opportunities

open access: yesInternational Journal of Digital Curation, 2018
Over the past decade, Qatar has been making considerable progress towards developing a sustainable research culture for the nation. The main driver behind Qatar’s progress in research and innovation is Qatar Foundation for Education, Science, and ...
Arif Shaon   +2 more
doaj   +1 more source

Introduction: new developments in Robert Burns bibliography [PDF]

open access: yes, 2017
Introduces four talks given at the National Library of Scotland on March 16, 2017, at a workshop on New Developments in Robert Burns Bibliography, jointly convened by Robert Betteridge of the National Library and by Prof. Carruthers, as general editor of
Carruthers, Gerard
core   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

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