Results 71 to 80 of about 8,906,651 (388)
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
VADR: validation and annotation of virus sequence submissions to GenBank
Background GenBank contains over 3 million viral sequences. The National Center for Biotechnology Information (NCBI) previously made available a tool for validating and annotating influenza virus sequences that is used to check submissions to GenBank ...
Alejandro A. Schäffer +6 more
doaj +1 more source
National Library of Malaysia Annual Report 2001 [PDF]
This Annual Report reflects the PNM activities during 2001, to support their vision,"The National Library of Malaysia aspires to be a world class library in the provision of excellent information services towards the realization of Malaysia's vision of ...
Noor, Norpishah Mohd.
core
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Setting up a National Research Data Curation Service for Qatar: Challenges and Opportunities
Over the past decade, Qatar has been making considerable progress towards developing a sustainable research culture for the nation. The main driver behind Qatar’s progress in research and innovation is Qatar Foundation for Education, Science, and ...
Arif Shaon +2 more
doaj +1 more source
National Security and National Library
The purpose of the study is to understand the mission of national library in the system of national security of Russia. The author formulates definition of national security basing on the analysis of state concepts and doctrines of national security.
openaire +2 more sources
The Impact Of Federal Legislation On Governmental And Special Libraries [PDF]
It has become increasingly obvious that libraries today cannot provide adequate service under conditions of local self-sufficiency. A variety of programs are required on the national level which cannot be provided by individual libraries or ...
Skipper, James E.
core
Digital reference services : a snapshot of the current practices in scottish libraries [PDF]
Discusses the current practices followed by some major libraries in Scotland for providing digital reference services(DRS). Refers to the DRSs provided by three academic libraries, namely Glasgow University Library, the University of Strathclyde Library,
Chowdhury, G., Margariti, S.
core +2 more sources
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
The State of The National Library of Nigeria: Why The Nigeria Government Must Act Fast. [PDF]
Nigeria, like many other developing countries, is passing through a critical period of educational, economic, political and social development. This established a truism that such development cannot be achieved in isolation.
Ejechi, Victor Tochukwu
core +1 more source

