Results 81 to 90 of about 8,906,651 (388)
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Eradicating Polio: 50 Years of Vaccines [PDF]
https://digitalcommons.cwu.edu/government_posters/1156/thumbnail ...
United States National Library of Medicine
core +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
To Your Health: An Exhibition of Posters for Contemporary Public Health Issues [PDF]
https://digitalcommons.cwu.edu/government_posters/1155/thumbnail ...
United States National Library of Medicine
core +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Supporting Rights Clearance for Digitisation Projects with the ARROW Service
The process of clearing the rights situation of a work for digitisation is very difficult to be performed for works that have been published during the 20th and 21st centuries.
Nuno Freire +3 more
doaj +1 more source
IFLA Congress in Italy for the fourth time , Libraries create futures: building on cultural heritage : final programme, Milan, Italy, 23-27 August 2009 [PDF]
Welcome of the Chair of the Italian National Committee. IFLA Congress comes back to Italy for the fourth time: 1929, 1951, 1964, and now 2009. In June 1929, in the Marciana Library (Venice), Mr.
Guerrini, Mauro
core
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Automatic Subject Cataloguing at the German National Library
The German National Library (DNB) began developing solutions for automatic subject cataloguing 15 years ago. The main reason for this was the huge and ever-growing number of digital media works that needed to be indexed.
Christoph Poley +6 more
doaj +1 more source

