Results 121 to 130 of about 1,333,689 (304)

Mechanoregulatory Effects of Cell‐Scale Microwells on Epithelial Cell Phenotype

open access: yesAdvanced Functional Materials, EarlyView.
In small polycaprolactone microwells, A549 epithelial cells span well edges, in contrast to cells growing on flat substrates. Focal adhesion sites (yellow) concentrate at topographic boundaries, while cytoskeletal tension (magenta stress fibers) is transmitted to the nucleus (blue), reducing nuclear sphericity.
Ruiwen He   +10 more
wiley   +1 more source

Large-scale predictions of alternative protein conformations by AlphaFold2-based sequence association

open access: yesNature Communications
The many successes of AlphaFold2 (AF2) have inspired methods to predict multiple protein conformations, many of which have biological significance.
Myeongsang Lee   +5 more
doaj   +1 more source

PublicationHarvester: An Open-Source Software Tool for Science Policy Research [PDF]

open access: yes
We present PublicationHarvester, an open-source software tool for gathering publication information on individual life scientists. The software interfaces with MEDLINE, and allows the end-user to specify up to four MEDLINE-formatted names for each ...
Andrew Stellman   +2 more
core  

Sensorized Engineered Tissues with Built‐in Thermoregulation and Nutrient Supply

open access: yesAdvanced Functional Materials, EarlyView.
This work introduces a granular hydrogel‐based tissue engineering platform that includes a closed‐loop temperature control to maintain 37°C and sustainably releases nutrients, thereby enabling cells to retain a high viability even if stored at room temperature for up to 24 h.
Antonia Georgopoulou   +5 more
wiley   +1 more source

A Dataset of Medical Questions Paired with Automatically Generated Answers and Evidence-supported References

open access: yesScientific Data
New Large Language Models (LLM)-based approaches to medical Question Answering show unprecedented improvements in the fluency, grammaticality, and other qualities of the generated answers.
Deepak Gupta   +2 more
doaj   +1 more source

Mechanochromism of Glassy Polymers Enabled by a Loop‐Forming Supramolecular Mechanophore

open access: yesAdvanced Functional Materials, EarlyView.
The supramolecular mechanophore LOOP is covalently introduced into glassy polymers, capable of reporting force‐induced pre‐failure damage and local fracture events in polymer glasses. Under different mechanical deformation modes, including grinding, tensile stretching, and scratching, LOOP probes irreversible events in polymer glasses through a ...
Linlin Deng   +6 more
wiley   +1 more source

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