Results 11 to 20 of about 1,333,689 (304)

Assessing Inter-Annotator Agreement for Medical Image Segmentation

IEEE Access, 2023
Artificial Intelligence (AI)-based medical computer vision algorithm training and evaluations depend on annotations and labeling. However, variability between expert annotators introduces noise in training data that can adversely impact the performance ...
Feng Yang, Ghada Zamzmi, Sandeep Angara, Sivaramakrishnan Rajaraman, Andre Aquilina, Zhiyun Xue, Stefan Jaeger, Emmanouil Papagiannakis, Sameer K. Antani   +8 more
doaj   +1 more source

High-throughput screening in larval zebrafish identifies novel potent sedative-hypnotics [PDF]

, 2018
BACKGROUND: Many general anesthetics were discovered empirically, but primary screens to find new sedative-hypnotics in drug libraries have not used animals, limiting the types of drugs discovered.
Brown, Lauren E., Dai, Jennifer B., Daigle, Renee, Forman, Stuart A., Halpin, Elizabeth S., Jounaidi, Youssef, Marte-Oquendo, Francisco, Porco, John A., Schaus, Scott E., Trilles, Richard, Xu, Wenqing, Yang, Xiaoxuan, Yu, Buwei   +12 more
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An historical overview of the National Network of Libraries of Medicine, 1985–2015

Journal of the Medical Library Association, 2018
The National Network of Libraries of Medicine (NNLM), established as the Regional Medical Library Program in 1965, has a rich and remarkable history.
Susan L. Speaker
doaj   +1 more source

VADR: validation and annotation of virus sequence submissions to GenBank

BMC Bioinformatics, 2020
Background GenBank contains over 3 million viral sequences. The National Center for Biotechnology Information (NCBI) previously made available a tool for validating and annotating influenza virus sequences that is used to check submissions to GenBank ...
Alejandro A. Schäffer, Eneida L. Hatcher, Linda Yankie, Lara Shonkwiler, J. Rodney Brister, Ilene Karsch-Mizrachi, Eric P. Nawrocki   +6 more
doaj   +1 more source

The medical science DMZ: a network design pattern for data-intensive medical science [PDF]

, 2017
: Objective We describe a detailed solution for maintaining high-capacity, data-intensive network flows (eg, 10, 40, 100 Gbps+) in a scientific, medical context while still adhering to security and privacy laws and regulations. Materials and Methods
Balas, Edward, Barnett, William, Berman, Ari, Cuff, James, Dart, Eli, Grossman, Robert L., Peisert, Sean, Shankar, Anurag, Tierney, Brian   +8 more
core   +1 more source

STAT: a fast, scalable, MinHash-based k-mer tool to assess Sequence Read Archive next-generation sequence submissions

Genome Biology, 2021
Sequence Read Archive submissions to the National Center for Biotechnology Information often lack useful metadata, which limits the utility of these submissions.
Kenneth S. Katz, Oleg Shutov, Richard Lapoint, Michael Kimelman, J. Rodney Brister, Christopher O’Sullivan   +5 more
doaj   +1 more source

Uncertainty Quantification in Segmenting Tuberculosis-Consistent Findings in Frontal Chest X-rays

Biomedicines, 2022
Deep learning (DL) methods have demonstrated superior performance in medical image segmentation tasks. However, selecting a loss function that conforms to the data characteristics is critical for optimal performance.
Sivaramakrishnan Rajaraman, Ghada Zamzmi, Feng Yang, Zhiyun Xue, Stefan Jaeger, Sameer K. Antani   +5 more
doaj   +1 more source

Strengthening and stretching for rheumatoid arthritis of the hand (SARAH). A randomised controlled trial and economic evaluation [PDF]

, 2015
Study registration: Current Controlled Trials ISRCTN 89936343.Background - The effectiveness of exercise for improving hand and wrist function in people with rheumatoid arthritis (RA) is uncertain.
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Developments in trapezium replacements

Orthopedic Reviews, 2017
The purpose of this update is to report on a variety of topics related to trapezium implants that have been investigated during the past three years. The keyword trapezium implant was utilized to query the PubMed database of the U.S.
Adam E.M. Eltorai, Alex Han
doaj   +1 more source

Assessing the National Library of Medicine’s Informationist Awards

Journal of eScience Librarianship, 2016
Objective: To understand the experience of the informationist recipients of NLM-funded Administrative Supplements for Informationist Services and gather evidence for their impact on NIH-funded biomedical research Methods: A mixed methods approach ...
Ariel Deardorff, Valerie Florance, Alan VanBiervliet   +2 more
doaj   +1 more source