Results 191 to 200 of about 473,849 (247)

Single‐Cell Transcriptomic Analysis of Tumor Heterogeneity and the Microenvironment in Pseudomyxoma Peritonei

Advanced Science, EarlyView.
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li, Lei Wang, Lei Ai, Zimeng Li, Zhaochangci Chen, Yuchen Luo, Tianran Zhang, Mengjia Liao, Songhao Wang, Jiajia Cui, Ke Liu, Chengxian Guo, Guodong Liu, Jiye Yin, Wei Wu   +14 more
wiley   +1 more source

Cyclic Mechanical Loading of Cardiomyocytes via Pressure‐Driven Non‐Planar Membrane Deformation in a Bioreactor System

Advanced Science, EarlyView.
In this research article, Mansoor and coworkers present a novel device that applies controlled mechanical stimuli to cardiomyocytes using pressure‐driven membrane deformation. By exposing cells to physiologically and pathologically relevant loading conditions, the platform reproduces distinct structural, functional and molecular responses associated ...
Haris Mansoor, Gabrielle Juul, Jil Patel, Heran Pradhan, Gram Hepner, Jackson Jewell, Mark Bardin, Ryan Slusser, Abigail Glezer, Leda Klouda, Melikhan Tanyeri, Anita Saraf   +11 more
wiley   +1 more source

Polychip‐A High‐Throughput Droplet Microfluidics Platform for Interrogating Microbial Interactions

Advanced Science, EarlyView.
Polychip, a fully integrated droplet microfluidics platform, enables high‐throughput, single‐cell resolution screening of polymicrobial interactions. By seamlessly combining six automated microfluidics operations on a single chip, the system accelerates antimicrobial discovery by 11 to 14 times compared to traditional robotic methods.
Jeong Jae Han, Adrian Ryan Guzman, Aifen Zhou, Han Zhang, Rohit Gupte, Haemin Jung, Kaylee Delgado, Sini Skariah, Ali Sultan, Arul Jayaraman, Paul de Figueiredo, Arum Han   +11 more
wiley   +1 more source

Clusters of Concern - Spatial Link between Childhood Undervaccination and Measles Outbreaks in South Carolina. [PDF]

N Engl J Med
Serman EA, Witrick B, Rennert L.
europepmc   +1 more source

Brenda Linares, MLIS, MBA, AHIP, Medical Library Association President, 2024-2025. [PDF]

J Med Libr Assoc
Nuñez AV, Flewelling K, Vardell E, Alpi KM.   +3 more
europepmc   +1 more source

Deep mutational scanning reveals the antibody escape and infectivity landscape of SARS-CoV-2 Omicron JN.1 and XEC receptor-binding domains. [PDF]

Emerg Microbes Infect
Shao C, Yang L, Xiao C, Huang Y, Wang X, Chen L, Liu P, Chen S, Wei M, Jia S, Cui L, Ge Y, Xu M, Jia X, Li J.   +14 more
europepmc   +1 more source

Enhanced Environmental PFAS Characterization Using a Virtual High-Resolution Mass Spectral Library Generated by Transfer Learning-Based Neural Network. [PDF]

Environ Sci Technol
Chen YC, Wu HY, Zhuang MN, Yi CM, Wu WS, Liao PC.   +5 more
europepmc   +1 more source

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The National Library of Medicine

Pediatrics, 1957
On October 1, 1956, the Armed Forces Medical Library was transferred to the Public Health Service and is now operating as the National Library of Medicine. An Act of Congress on August 3, 1956, places the Library under the Surgeon General of the Public Health Service.
exaly   +2 more sources