Results 111 to 120 of about 3,273,344 (325)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Dermatitis atópica: fisiopatología y sus implicaciones clínicas

Correo Científico Médico, 2020
La dermatitis atópica, enfermedad crónica multifactorial inflamatoria de la piel, presenta una fisiopatología compleja multifactorial y no bien conocida donde factores genéticos y ambientales se interrelacionan para favorecer su desarrollo.
María de los Angeles Leyva Montero, Yarimi Rodríguez Moldón, Raisa Rodríguez Duque, Sara Marjorie Mejia Alcivar, Lam Layhyong Luyo Joza   +4 more
doaj  

MEDICATION ERRORS IN PEDIATRICS AND PREVENTION STRATEGIES: AN INTEGRATIVE REVIEW

Cogitare Enfermagem, 2017
An integrative review was undertaken to analyze the strategies, safety incidents and the phase of the medication process intended to prevent adverse events in pediatrics. Data collection took place between November/2015 and February/2017 in the databases:
Bárbara Monteiro Volpatto, Wiliam Wegner, Luiza Maria Gerhardt, Eva Neri Rubim Pedro, Silvana da Silva Cruz, Larissa Edom Bandeira   +5 more
doaj   +1 more source

Rerendering Semantic Ontologies: Automatic Extensions to UMLS through Corpus Analytics [PDF]

LREC 2002 Workshop on Ontologies and Lexical Knowledge Bases, 2002
In this paper, we discuss the utility and deficiencies of existing ontology resources for a number of language processing applications. We describe a technique for increasing the semantic type coverage of a specific ontology, the National Library of Medicine's UMLS, with the use of robust finite state methods used in conjunction with large-scale corpus
arxiv  

Special Libraries, May-June 1977 [PDF]

, 1977
Volume 68, Issue 5-6https://scholarworks.sjsu.edu/sla_sl_1977/1004/thumbnail ...
Special Libraries Association
core   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

A relação das áreas cerebrais com o transtorno de personalidade antissocial: revisão integrativa

Revista de Saúde Pública do Paraná
O transtorno de personalidade antissocial (TPA) é relacionado às variações estruturais e funcionais das regiões cerebrais. Frente a isso, buscou-se, por meio da revisão integrativa da literatura, verificar o que a literatura aponta como alterações ...
Hannara Andrade Gabina Oliveira
doaj   +1 more source

Information Outlook, May 2006 [PDF]

, 2005
Volume 10, Issue 5https://scholarworks.sjsu.edu/sla_io_2006/1004/thumbnail ...
Special Libraries Association
core   +3 more sources

A review of artificial intelligence in brachytherapy

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Artificial intelligence (AI) has the potential to revolutionize brachytherapy's clinical workflow. This review comprehensively examines the application of AI, focusing on machine learning and deep learning, in various aspects of brachytherapy.
Jingchu Chen, Richard L. J. Qiu, Tonghe Wang, Shadab Momin, Xiaofeng Yang   +4 more
wiley   +1 more source