Results 51 to 60 of about 584,455 (290)

Septicemia in a Neonate following Therapeutic Hypothermia: The Literature Review of Evidence

open access: yesCase Reports in Pediatrics, 2013
We report a term neonate with hypoxic ischemic encephalopathy who underwent a 72-hour therapeutic hypothermia. He developed unstable body temperature associated with coagulase negative staphylococcus septicemia 2 weeks later which was promptly treated ...
Kam Lun Hon   +3 more
doaj   +1 more source

Open Access in the United States [PDF]

open access: yes, 2006
A survey of the most important, current open-access projects in the United ...
Suber, Peter
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

About the MeSH information and retrieval query language in the area of activity of Polish academic libraries of medical universities

open access: yesForum Bibliotek Medycznych
The article presents the history of MeSH, the information and retrieval query language in Poland, in the context of cooperation between academic medical libraries. It also discusses the role of the Central Medical Library in the implementation of medical
Magdalena Kotlarek-Naskręt
doaj   +1 more source

Prevalence of body weight dissatisfaction among adolescents: a systematic review

open access: yesRevista Paulista de Pediatria, 2022
Objective: To identify the prevalence of weight dissatisfaction among adolescents aged 10-19 years and stratify the analysis by sex. Data source: A literature review of cross-sectional studies among healthy adolescents was performed. The U.S. National
Mariana Contiero San Martini   +4 more
doaj   +1 more source

Examining Moral Hazard in the Healthcare Insurance Market [PDF]

open access: yes, 2018
This study aims to examine the effect of insurance coverage on medical expenditure in the United States. The data was gathered from the Household Component Medical Expenditure Panel Survey and is a cross-sectional data set with a sample size of ...
Ashby, Samuel
core   +1 more source

Instrumentation [PDF]

open access: yes, 1953
published or submitted for ...
Gull, C.D.
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

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