Results 231 to 240 of about 159,174 (307)

The licensing responsibilities for the pilot fuel plant (PFP) in ensuring safety as required by the National Nuclear Regulator (NNR) in order to obtain an operating licence

, 2006
MSc (Applied Radiation), North-West University, Mafikeng Campus Any industrial activity yields benefits and incurs risks, and the nuclear industry is not different. The risks may be borne by the site personnel, by people living near the installation and by the whole of society.
openaire   +1 more source

PD‐L1‐Binding Antigen Presenters: Redirecting Vaccine‐Induced Antibodies for Cancer Immunotherapy

Advanced Science, EarlyView.
The PBAP‐gE complex anchors gE antigen to PD‐L1 on tumor cells. Vaccine‐induced anti‐gE antibodies simultaneously engage FcγRIIIa on NK cells and tumor‐bound PBAP‐gE, triggering NK cell activation and antibody‐dependent cellular cytotoxicity, thereby selectively eliminating PD‐L1–expressing tumor cells.
Huixin Gao, Lijuan Lu, Xiaoxiao Xiong, Yi Li, Donghui Hu, Duo Zhang, Zhiwei Feng, Cong Liu, Nannan Liu, Xiaoli Li, Jizhou Tan, Ting Liu, Ling Peng, Lu Lu, Huiyi Feng, Yan Zhong, Guisen Tan, Zhicheng Zhang, Liqin Huang, Chao Su, Ying Xue, Shuo Song, Wenxia Fan, Wei Wang, Fan Zou   +24 more
wiley   +1 more source

Metabolomic changes in the peripheral blood of wild trapped badgers (Meles meles) correlate with bovine tuberculosis (Mycobacterium bovis) infection status. [PDF]

BMC Vet Res
Scott-Baumann J, Beckmann M, Villarreal-Ramos B, Rooke D, Hewinson G, Delahay RJ, Mur LAJ.   +6 more
europepmc   +1 more source

miR‐135a‐5p Is a Promising Target to Prevent the Glomerulosclerosis Associated with Podocyte Developmental Toxicity in Offspring Induced by Prenatal Dexamethasone Exposure

Advanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) programs persistent podocyte developmental injury and adult glomerulosclerosis. Mechanistically, glucocorticoid receptor (GR) binds the miR‐135a‐5p promoter and recruits the histone acetyltransferase p300, increasing promoter histone acetylation and sustaining miR‐135a‐5p expression. Elevated miR‐135a‐5p suppresses
Xiaoqi Zhao, Haiyun Chen, Yanan Zhu, Zhiping Xia, Hangyuan He, Yutang Liu, Tianshu Yang, Hui Wang, Ying Ao   +8 more
wiley   +1 more source

Private Keeping of Dangerous Wild Animals in Great Britain. [PDF]

Animals (Basel)
Draper C, Lewis C, Jayson S, Osuch F.
europepmc   +1 more source

Immigration: The points based system – student routes [PDF]

, 2012

core  

ZBTB21 Is a Dual Suppressor of Pyroptosis and MHC‐I Antigen Presentation That Promotes Tumor Immune Evasion

Advanced Science, EarlyView.
ZBTB21 is a transcription factor that epigenetically suppresses pyroptosis and MHC‐I antigen presentation, enabling tumor immune evasion. Genetic ablation of ZBTB21 activates pyroptotic cell death and enhances antigen presentation, recruiting CD8+ T cells to overcome immune checkpoint blockade resistance.
Lei Zhao, Linlin Sheng, Jianhao Qiu, Junjie Ma, Kai Jin, Binggong Zhao, Tianrun Miao, Jing Chen, Yehong Li, Zhan Zhang, Dongfeng Sun, Yongmeng Li, Hui Tian   +12 more
wiley   +1 more source

Risk Factors for Liver Disease Cluster Geographically: A Precision Public Health Analysis of a UK City. [PDF]

Aliment Pharmacol Ther
Parker R, Taylor A, Dukes R, Wilks B, Hinkson A, Burn D, Rowe IA.   +6 more
europepmc   +1 more source

Identification of Mannose‐Capped‐Arabinomannan 101‐mer as a Potential Influenza Virus Vaccine Adjuvant

Advanced Science, EarlyView.
Well‐defined and synthetic mannose‐capped arabinomannan 101‐mer from Mycobacterium tuberculosis cell wall was identified as a potent influenza vaccine adjuvant, boosting the antibody response, realizing full protection and showing excellent safety. ABSTRACT Many natural bacterial components as adjuvants can activate the host immune system, but the ...
Yu‐Fang Zhang, Ruihong Xu, Jia Luo, Yuxin Ma, Guozhi Xiao, Ye Liu   +5 more
wiley   +1 more source

Naval sonar induces an anaerobic swimming gait in beaked whales. [PDF]

Sci Rep
Martín López LM, Isojunno S, Cade D, Colson K, Paradinas I, Miller PJO, Fahlman A, Hickmott LS, Visser F.   +8 more
europepmc   +1 more source