Results 241 to 250 of about 159,174 (307)

A Metal‐Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer

open access: yesAdvanced Science, EarlyView.
A metal‐free carbon monoxide (CO) prodrug, CO‐116, delivers controlled systemic CO without inhalation. CO suppresses the HRG1–heme axis, reducing intracellular heme availability. Attenuation of this pathway inhibits metastatic progression in pancreatic and triple‐negative breast cancer models.
Tiantian Zhang   +15 more
wiley   +1 more source

Xanthatin Targets CISD1 to Drive Ferroptosis and Mitophagy as a Dual Anticancer Strategy in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
Triple‐negative breast cancer has a poor prognosis. Xanthatin directly targets and degrades CISD1, triggering ferroptosis through iron dysregulation. The concurrently activated mitophagy synergistically amplifies ferroptotic cell death. Xanthatin also demonstrates potent in vivo anti‐tumor efficacy with minimal toxicity, highlighting its therapeutic ...
Qinwen Liu   +9 more
wiley   +1 more source

A Practical treatise on the law of nations, relative to legal effect of war on the commerce of belligerents and neutrals; and on Orders in council and licences.

open access: yesA Practical treatise on the law of nations, relative to legal effect of war on the commerce of belligerents and neutrals; and on Orders in council and licences.
identifier:https://repository.tku.ac.jp/dspace/handle/11150 ...
openaire  

Pan‐3D Genome Analysis Reveals the Roles of Structural Variation in Chicken Chromatin Architectures, Domestication and Production Traits

open access: yesAdvanced Science, EarlyView.
This study firstly presents a comprehensive and high‐resolution pan‐3D genome resource in chicken. Our findings reveal the role of structural variations in 3D genome architectures, and how they influence the domestication process and production traits at the 3D genome level.
Zhen Zhou   +19 more
wiley   +1 more source

Assessing semantic interoperability in environmental sciences: variety of approaches and semantic artefacts. [PDF]

open access: yesSci Data
Di Muri C   +9 more
europepmc   +1 more source

Evaporation‐Driven Solutal Marangoni Control of Rayleigh–Taylor Instability in Inverted Films

open access: yesAdvanced Science, EarlyView.
Inverted liquid films, like paint on a ceiling, are inherently unstable under gravity. This work shows that selective evaporation in volatile binary mixtures generates solutal Marangoni stresses that either suppress or amplify the Rayleigh Taylor instability.
Minwoo Choi, Hyejoon Jun, Hyoungsoo Kim
wiley   +1 more source

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