Results 141 to 150 of about 6,946,553 (358)
Transatlantic consumptions: disease, fame and literary nationalisms in the Davidson sisters, Southey, and Poe. [PDF]
This article supplements Lawlor’s Consumption and Literature by demonstrating the complex relationships between disease and literature. Lawlor shows how the consumptive American poetesses, sisters Margaret and Lucretia Davidson, became famous for their ...
Lawlor, Clark
core
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Tożsamość kulturowa w rusińskiej literaturze na Słowacji
Cultural identity is a very important part of national identity, as it defines the individual’s place in society. The aim is to show the Rusyn national identity consolidated in the contemporary literary works and to define the symbolism used by the Rusyn
Ivana Slivková
doaj
We review the literature on national innovation systems. We first focus on the emergence of the concept of innovation systems, reviewing its historical origins and three main flavours (associated to three “founding fathers†of the concept). After this,
B. Verspagen, Bas ter Weel, L. Soete
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
This paper is an offshoot of a larger, ongoing project that intends to deal with the relationship between various artistic formations and the dominant culture in Taiwan\u27s post-1949 era. Though the lifting of martial law in 1987 has demarcated this era
CHANG, Sung Sheng, Yvonne
core
Effects of New Zealand general elections on stock market returns [PDF]
This paper examines stock returns under both National and Labour governments in New Zealand, offering further insight into the existence of the political cycle effect.
Abidin, Sazali Zainal +2 more
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Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source

