Results 101 to 110 of about 869,846 (294)

TGF-β1/p65/MAT2A pathway regulates liver fibrogenesis via intracellular SAMResearch in context

EBioMedicine, 2019
Background: Hepatic stellate cell (HSC) activation induced by transforming growth factor β1 (TGF-β1) plays a pivotal role in fibrogenesis, while the complex downstream mediators of TGF-β1 in such process are largely unknown.
Kuifeng Wang, Shanhua Fang, Qian Liu, Jing Gao, Xiaoning Wang, Hongwen Zhu, Zhenyun Zhu, Feihong Ji, Jiasheng Wu, Yueming Ma, Lihong Hu, Xu Shen, Daming Gao, Jiansheng Zhu, Ping Liu, Hu Zhou   +15 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

through ecological shifts [PDF]

, 2020
[EN] Despite the role of polyploidy in multiple evolutionary processes, its impact on plant diversification remains controversial. An increased polyploid frequency may facilitate speciation through shifts in ecology, morphology or both.
Ting‐Shen Han, Yao‐Wu Xing, Frank Hauenschild, Blanca M. Rojas‐Andrés, Hauenschild, Frank, Han, Ting‐Shen, Rojas Andrés, Blanca M., Muellner‐Riehl, Alexandra N., Quan‐Jing Zheng, Xing, Yao‐Wu, Zheng, Quan‐Jing, Alexandra N. Muellner‐Riehl, Renske E. Onstein, Onstein, Renske E.   +13 more
core   +1 more source

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han, Jiachun Pan, Yuehui Hong, Xiaoyuan Fan, Ming Yao, Lixin Zhou, Yicheng Zhu, Feng Feng, Jun Ni   +8 more
wiley   +1 more source

Exploring the impact of core expansion on the vortex distribution in superconducting-normal-metal hybrid nanostructures

, 2019
sponsorship: R.P., B.R, V.V.M., and J.V.d.V. acknowledge support from the Methusalem funding by the Flemish government and the Flemish Science Foundation (Grant No. G0B5315N). C.X. acknowledges support by the National Natural Science Foundation of China (
Panghotra, Ritika, Vondel, Joris van de, Van de Vondel, Joris, Xue, Cun, Moshchalkov, V.V., Timmermans, Matias, Raes, Bart, Moshchalkov, Victor   +7 more
core   +1 more source

In-situ SEM study of fatigue micro-crack initiation and propagation behavior in pre-corroded AA7075-T7651

, 2020
Fatigue micro-cracking behavior in pre-corroded AA7075-T7651 is analyzed by in-situ scanning electron microscopy (SEM) observation and SEM-based fractography.
Yang, Xudong, Leen, Sean B., Liu, Changchun, Du, Juan, Song, Haipeng, Zhang, Hao   +5 more
core   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source

Amine-functionalized covalent organic frameworks for high-performance carbon dioxide capture

[EN] Covalent organic frameworks (COFs) have garnered significant interest as advanced platforms for carbon capture, utilization, and storage, owing to their high surface area, tunable porosity, and excellent chemical stability.
Zhao, Feifan, García Gómez, Hermenegildo, Xu, Feiyan, Yu, Jiaguo   +3 more
core   +1 more source

China’s most typical nonferrous organic-metal facilities own specific microbial communities [PDF]

, 2018
This is the final version of the article. Available from Springer Nature via the DOI in this record.The diversity and function of microorganisms have yet to be explored at non-ferrous metal mining facilities (NMMFs), which are the world’s largest and ...
Hudson-Edwards, KA, Liu, Xing-yu, Hudson-Edwards, Karen A., Yao, J, Sunahara, Geoffrey, Duran, R, Wang, F, Jordan, G, Alakangas, Lena, Alakangas, L, Ni, W, Šolević Knudsen, Tatjana, Solevic-Knudsen, T, Liu, W-Y, Zhang, Yi-yue, Ni, Wen, Li, Z-F, Duran, Robert, Yao, Jun, Li, Zi-fu, Sunahara, G, Wang, Fei, Liu, Jian-li, Jordan, Gyozo, Hudson-Edwards, Karen, Liu, J-L, Zhang, Y-Y, Zhu, Xiao-zhe, Solevic-Knudsen, Tatjana, Zhu, X-Z   +29 more
core   +1 more source

Understanding the antagonistic effect of methanol as a component in surrogate fuel models: A case study of methanol/n-heptane mixtures

, 2021
Methanol is a widely used engine fuel, blend component, and additive. However, no systematic auto-ignition data or laminar flame speed measurements are available for kinetic studies of the effect of methanol as a blending or additive component.
Mohamed, Ahmed Abd El-Sabor, Tang, Chenglong, Bariki, Chaimae, Sahu, Amrit B., Wu, Yingtao, Curran, Henry J., Mohamed, Ahmed A. E., Pitsch, Heinz, Panigrahy, Snehasish, Liang, Jinhu, Huang, Zuohua, Beeckmann, Joachim, Dong, Shijun   +12 more
core   +1 more source