Results 191 to 200 of about 880,844 (243)

Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis

Advanced Science, EarlyView.
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang, Jianhua Li, Huilu Zhang, Qi Qin, Yichen Huang, Xiaofan Tian, Chao Sun, Binbin Li, Zhengxin Wang, Xin Zhang   +9 more
wiley   +1 more source

Correction: Machine-assisted adaptive feedback consensus method for large-scale group decision making based on reinforcement learning. [PDF]

Front Big Data
Yu H, Xu X, Zhang W.
europepmc   +1 more source

Gonadotropin‐Inhibitory Hormone (GnIH) and Its Receptor GPR147 Mediates Acute Stress‐Induced Activation of the Locus Coeruleus‐SAM Axis

Advanced Science, EarlyView.
ABSTRACT Gonadotropin‐inhibitory hormone (GnIH, also known as RFamide‐related peptide‐3, RFRP‐3) is a hypothalamic neuropeptide that regulates vertebrate reproduction via its receptor GPR147. Although GnIH is known to mediate stress‐induced reproductive suppression, its role in broader stress responses remains unclear.
Jiani Zhang, Hongyu Zhu, Wenqi Wang, Bingqian Shen, Yuanyuan Xin, Xingxing Song, Xuanyi Lu, Lixuan Li, Siting Chen, Xiaochen Zhang, Jialing Zeng, Haodong Zheng, Jianlong Lao, Ke Peng, Yixian Wei, Jiaming Zheng, Chuanhuo Hu, Xiaoye Wang, Xun Li   +18 more
wiley   +1 more source

Pulmonary Hamartoma Diagnosed by Transbronchial Mediastinal Cryobiopsy Additional to Needle Aspiration: A Case Report. [PDF]

Respirol Case Rep
Shou XY, Fu WL, Huang ZS, Zhang SX, Zhao J, Zhang J, Herth FJF, Fan Y.   +7 more
europepmc   +1 more source

Integrating Genetics With Epidemiological Measurements Identifies Burden QTLs of Inflammatory Bowel Disease across 20 Countries

Advanced Science, EarlyView.
The burden quantitative trait locus (bQTL) analysis integrates epidemiological data from GBD study with genotype of 2 621 978 SNPs from 2414 individuals in 1000 Genomes Project across 20 countries. rs7633471 shows the strongest effect that each increase in centi‐allele frequency of the allele C associated with 10.00 decrease of age‐standardized ...
Chen Sun, Siyu Wei, Junxian Tao, Haiyan Chen, Chi Yan, Jiacheng Wang, Jing Xu, Lian Duan, Yuanbo Zhan, Yuping Zou, Ruilin Li, Linna Yuan, Wei She, Songlin Lu, Ning Wang, Qinduo Ren, Yan Guo, Yuan Xu, Chang Wang, Hongsheng Tian, Chen Zhang, Yu Dong, Guoping Tang, Zhenwei Shang, Yongshuai Jiang, Wenhua Lv, Mingming Zhang, Hongchao Lyu   +27 more
wiley   +1 more source

SlExp1 Genetically Interacts With Cell Wall-Modifying Enzymes to Coordinate Tomato Fruit Softening. [PDF]

Plant Biotechnol J
Zhang K, Wang C, He Z, Shu X, Lin Y, Su G, Shao Z, Lin X, Blanco-Ulate B, Zheng J, Shi Y, Chen K.   +11 more
europepmc   +1 more source

A Soft, Flexible Implant for Wireless Photothermal–Pyroelectric Neurostimulation

Advanced Science, EarlyView.
A replication strategy is used to enlarge the exposed surface area of barium titanate within flexible films with embedded carbon nanotubes, enabling efficient photothermal‐pyroelectric stimulation. Polar crystalline nanosheets show superior performance in guiding neural progenitor cells toward neuronal differentiation.
Jiang Wu, Minmin Mao, Beltzane Garcia Cirera, Hao Ye, Xiangzhong Chen, Josep Puigmartí‐Luis, Ni Qin, Salvador Pané   +7 more
wiley   +1 more source

Self-charged toothbrush facilitates tooth healthcare maintenance. [PDF]

Sci Adv
Lu Y, Song J, Chi X, Li W, Wu L, Guo Y, Cui Q, Zheng X, Bai Y, Heng BC, Han X, Zhang X, Deng X.   +12 more
europepmc   +1 more source

Correction: Intermediate knowledge enhanced the performance of the amide coupling yield prediction model. [PDF]

Chem Sci
Zhang C, Lin Q, Yang C, Kong Y, Yu Z, Liao K.   +5 more
europepmc   +1 more source

Superionic Al─O─H Compounds With Unconventional Stoichiometries Under Extreme Planetary Conditions. [PDF]

Adv Sci (Weinh)
Wang Z, Shim JH, Kim DY.
europepmc   +1 more source