Results 221 to 230 of about 773,170 (362)

Efficacy and Safety Assessment of 5‐Fluorouracil, Irinotecan and Oxaliplatin‐Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy

open access: yesAdvanced Materials, EarlyView.
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade   +19 more
wiley   +1 more source

Language concordance in the digital collection of patient-reported outcome measures. [PDF]

open access: yesJAMIA Open
Liu JB   +7 more
europepmc   +1 more source

Electric‐Current‐Assisted Nucleation of Zero‐Field Hopfion Rings

open access: yesAdvanced Materials, EarlyView.
This work reports a novel and efficient nucleation protocol for 3D localized topological magnetic solitons‐hopfion rings in chiral magnets using pulsed electric currents. By using Lorentz transmission electron microscopy and topological analysis, we report characteristic features and extraordinary stability of hopfion rings in zero or inverted external
Xiaowen Chen   +12 more
wiley   +1 more source

Evaluation of large Language model performance on Persian rheumatology board exams: accuracy and clinical reasoning of GPT-4o vs. GPT-5.1. [PDF]

open access: yesSci Rep
Rafiei F   +8 more
europepmc   +1 more source

High‐Throughput 3D Matrigel‐based Droplet Microfluidics for Single‐Cell Function‐to‐Omics Analysis of Cytotoxic Immune Cells in Solid Tumor Interactions

open access: yesAdvanced Materials Technologies, EarlyView.
A 3D Matrigel‐based droplet microfluidics platform that allows physiologically relevant analysis of single immune‐tumor interactions in solid tumors. By integrating real‐time functional imaging with fluorescence‐activated droplet sorting and RNA sequencing, the system links immune cytotoxic behavior to transcriptomic profiles, providing a scalable ...
Christina Sharkey   +6 more
wiley   +1 more source

BLOC: Buildable and Linkable Organ on a Chip

open access: yesAdvanced Materials Technologies, EarlyView.
We developed a “Buildable and Linkable Organ on a Chip” (BLOC) that can construct diverse microphysiological systems (MPSs). The BLOC is standardized to the same size and has one of the functions of “Culture,” “Control,” or “Analysis.” Users can freely configure various MPSs, including developing perfusion, cytotoxicity analysis, and biochemical ...
Yusuke Kimura   +7 more
wiley   +1 more source

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