Results 121 to 130 of about 8,385,307 (350)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Path dependence in technologies and organizations: a concise guide [PDF]

open access: yes
The note on which an entry for the Palgrave Encyclopedia of Strategic Management will draw offers a beginner’s guide to path dependency in technologies and organizations. We address the very meaning of the concept and its centrality in various aspects of
Giovanni Dosi   +2 more
core   +3 more sources

Editorial requests to support an Appalachian National Park [PDF]

open access: yes, 2015
In this series of letters, the Appalachian National Park movement requests various people and organizations to write articles about their cause. In promoting a national park in the southern Appalachians, Chase Ambler wrote dozens of editorials, including
Holmes, J. A. (Joseph Austin), 1859-1915; Beadle, Chauncey D. (Chauncey Delos), 1866-1950; Haight, R. J. (Rufus J.); Ambler, Chase P., 1865-1932; Ashe, W. W. (William Willard), 1872-1932; Appalachian National Park Association;
core  

MULTI-CRITERIA APPROACH FOR DEVELOPING STAKEHOLDER-ORIENTED STRATEGIES IN TOURISM ENTERPRISE MANAGEMENT

open access: yesФінансово-кредитна діяльність: проблеми теорії та практики
This study develops a stakeholder-oriented strategy for tourism enterprise management using a multi-criteria decision-making approach. The research focuses on evaluating and prioritising stakeholder preferences to align enterprise objectives with their ...
Оксана Роїк   +4 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

QUALITY PRODUCTS EXAMINATION AT CLOSED-CYCLE INDUSTRIES NUCLEAR POWER PLANT STRUCTURAL MATERIALS

open access: yesНадежность и качество сложных систем
Background. The article considers the way to solve the urgent problem of expertise and quality testing of specific products of original production facilities for the utilization of dismantled structural elements of nuclear power plants during their ...
A.S. Grigoriev   +3 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Insuring Consumption and Happiness Through Religious Organizations [PDF]

open access: yes
This paper examines whether involvement with religious organizations insures an individual's stream of consumption and of happiness. Using data from the Consumer Expenditure Survey (CEX), we examine whether households who contribute to a religious ...
Rajeev Dehejia   +2 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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