Results 211 to 220 of about 564,338 (259)

Bone weathering in a Mediterranean climate region: An experimental case study from Doñana National Park (Spain). [PDF]

open access: yesPLoS One
Pizarro-Monzo M   +5 more
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

High prevalence of Trypanosoma spp. and apparent trypanocidal drugs inefficacy in cattle in Al Radom National Park, Sudan. [PDF]

open access: yesSci Rep
Mohammedsalih KM   +9 more
europepmc   +1 more source

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