Results 31 to 40 of about 1,279,446 (308)

Type I Interferon Pathway Activation Disrupts Monocyte Maturation and Enhances Immune Evasion in Multiple Myeloma

Advanced Science, EarlyView.
This study shows that monocytes in multiple myeloma display an excessive interferon response, leading to transcriptional reprogramming and altered differentiation. Using single‐cell sequencing, coculture experiments, and patient samples before and after therapy, the authors demonstrate that induction treatment reduces this interferon response ...
Jian Cui, Jingwei Wang, Xiaoyun Li, Lina Wang, Xuehan Mao, Rui Lyv, Wenqiang Yan, Jingyu Xu, Jieqiong Zhou, Chenxing Du, Shuhui Deng, Mu Hao, Yan Xu, Shuhua Yi, Dehui Zou, Tao Cheng, Xin Gao, Lugui Qiu, Gang An   +18 more
wiley   +1 more source

Legal Regulation of the Activities of the Bodies of the National Police of Ukraine on Ensuring the Exercise of the Right to Freedom of Peaceful Assembly

Bulletin of Kharkiv National University of Internal Affairs, 2019
Under the conditions set out in Part 2 of Art. 19 of the Constitution of Ukraine of the legal order in Ukraine, according to which state bodies to which the National Police of Ukraine belongs, their officials are obliged to act only on the basis, within ...
M. A. Sambor
doaj   +1 more source

Increasing the combat readiness and fighting capacity of police officers to act in extreme situations

Law and Safety, 2022
The high level of injuries and the number of cases of death of law enforcement officers, especially in extreme situations, require constant and in-depth research in the field of improving the professional abilities of law enforcement officers.
I. V. Vlasenko, T. V. T. V. Shevchenko
doaj   +1 more source

The challenges of change:Exploring the dynamics of police reform in Scotland [PDF]

, 2019
Despite a long tradition of pessimism regarding the scope for meaningful change in police practices, recent structural reforms to police organizations in several European countries suggest that significant change in policing is possible.
Donnelly D, Fyfe NR, Fyfe NR, Fyfe NR, Fyfe NR, Fyfe NR, Fyfe NR, Her Majesty’s Inspectorate of Constabulary in Scotland (HMICS), Loader I, Marshall C, Murray K, Nicholas R. Fyfe, Police Scotland, Savage S, Scottish Government, Scottish Government, Scottish Police Authority, Scottish Police Authority, Scottish Police Authority, SIPR, Scotcen and What Works Scotland, SIPR, Scotcen and What Works Scotland, SIPR, What Works Scotland and Scotcen, SIPR, What Works Scotland and Scotcen, SIPR, What Works Scotland and Scotcen, Sparrow M, Terpstra J   +25 more
core   +3 more sources

Iron Oxide Nanozyme as Reactive Oxygen and Nitrogen Species Scavenger to Regulate Microglial Homeostasis in Stroke

Advanced Science, EarlyView.
6 nm iron oxide nanoparticles (IONP6) exhibit enzyme‐like activities that scavenge reactive oxygen and nitrogen species (RONS), including nitric oxide (NO). In stroke models, IONP6 promotes microglial polarization toward the M2 phenotype, reduces neuroinflammation, and improves neurological outcomes, offering a promising drug‐free approach to mitigate ...
Yilin Qi, Chunxiao Wang, Yuqing Miao, Jiamin Li, Zengyu Xun, Di Sun, Fei Xu, Minrui Liu, Heping Wang, Galong Li, Xuyi Chen, Haiming Fan, Xue Xue   +12 more
wiley   +1 more source

COMPETENCE IMPROVEMENT OF POLRI EDUCATORS THROUGH SPREADING TRAINING

Empowerment, 2018
The development of science and technology today demands changes and a better and more mature working mechanism in anticipating every challenge in the community. This also applies to the Indonesian National Police.
Mamay Sumarna
doaj   +1 more source

Increasing Police Accountability and Improving Use of Force Policies in the United States [PDF]

, 2018
Communities, and their respective police departments, have significant impacts on the social and legal matters they are involved with, making it crucial for both parties to strive to maintain strong, collaborative relationships.
Kwong, Leica
core   +1 more source

A Subset of Pro‐inflammatory CXCL10+ LILRB2+ Macrophages Derives From Recipient Monocytes and Drives Renal Allograft Rejection

Advanced Science, EarlyView.
This study uncovers a recipient‐derived monocyte‐to‐macrophage trajectory that drives inflammation during kidney transplant rejection. Using over 150 000 single‐cell profiles and more than 850 biopsies, the authors identify CXCL10+ macrophages as key predictors of graft loss.
Alexis Varin, Jovanne Palvair, Lennie Messager, Jamal Bamoulid, Jasper Callemeyn, Mélanie Chaintreuil, Ludivine Dal Zuffo, Didier Ducloux, Imane Farhat, Mathieu Legendre, Laurent Martin, Florian Renosi, Xavier Roussel, Thibaut Vaulet, Maarten Naesens, Claire Tinel, Baptiste Lamarthée   +16 more
wiley   +1 more source

Current directions for improving the administrative, legal and organisational principles of the activities of higher education institutions of the MIA of Ukraine which provide police training, taking into account the requirements of martial law

Bulletin of Kharkiv National University of Internal Affairs, 2023
The authors have studied the legal and organisational framework for the activities of higher education institutions of the Ministry of Internal Affairs of Ukraine which provide police training.
K. L. Buhaichuk, O. A. Morhunov
doaj   +1 more source

Electric‐Field‐Driven Bilayer Interphase from Oxygenated Nanodiamond‐Carbon Nanoparticles for Dendrite‐Free Lithium Metal Batteries

Advanced Energy Materials, EarlyView.
Electric‐field‐driven carbon migration within an oxygen‐functionalized nanodiamond/carbon composite induces the formation of a vertically graded interphase that homogenizes Li‐ion flux and suppresses dendritic nucleation. This hierarchically organized structure stabilizes the electrode–electrolyte interface and delivers durable, dendrite‐free operation
Jaeseong Kim, Incheol Heo, Dong‐Kyung Kim, Min Seok Kang, Ji Hee Kwon, Byeong‐Seon An, Keir C. Neuman, Byung‐Hyun Kim, Hak‐Sung Jung, Won Cheol Yoo   +9 more
wiley   +1 more source