Results 181 to 190 of about 23,506,758 (249)

Zimbabwean youth with disabilities in Technical Vocational Education and Training: An institutional ethnography. [PDF]

Afr J Disabil
Goteka M, Munambah NE, van Niekerk L, Ned L.   +3 more
europepmc   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Exploring the current status of pharmacist prescribing in Middle Eastern Arab countries: a scoping review. [PDF]

Int J Clin Pharm
Alajmi RH, Barry HE, Almalag HM, Hughes CM.   +3 more
europepmc   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Skills-Based Human Capital Management in Latvian University Hospitals: A Qualitative Multi-Institutional Study. [PDF]

Healthcare (Basel)
Grigoroviča E, Slavinska A, Bahs G, Muravska T, Edelmers E.   +4 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

National Dental Commission - Toward a Collaborative and Outcome-driven Approach. [PDF]

Int J Appl Basic Med Res
Sekhri K, Nandha R.
europepmc   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Does Allostatic Load in 50-89-Year-Olds Predict the Development of Frailty? Evidence From a National Longitudinal Study Over 12 Years. [PDF]

Stress Health
Arkesteijn M, Bennett R, Davies JL, Sumner RC.   +3 more
europepmc   +1 more source