Results 31 to 40 of about 9,802 (265)

Discovery of H2 Receptor Antagonists as Colistin Enhancers by Targeting Acid Stress Response

Advanced Science, EarlyView.
This study identifies YqgB as a key target for restoring colistin susceptibility in mcr‐positive pathogens under acidic conditions by remodeling phospholipid composition and reducing LPS modification. Deep learning‐based screening reveals H2 receptor antagonists as novel colistin adjuvants. Further investigations indicate that ranitidine and famotidine
Jinju Cai, Mengping He, Jianya Luo, Shuang Zhou, Tengyue Zhang, Jianing Li, Zhiqiang Wang, Yuan Liu   +7 more
wiley   +1 more source

The role of the orthodox clergy of the Right Bank Ukraine in the protection of the rights and freedoms of the peasantry (second half of the 19th – the beginning of the 20th century)

Науковий вісник Чернівецького національного університету імені Юрія Федьковича. Історія, 2020
In the middle of the 19th century among the Orthodox clergy of the Ukrainian dioceses of the ROC, there was a clear division between the Orthodox, who served the interests of the autocracy and opposed the reforms of the church and its ukrainization, and
Олексій Кошель
doaj  

Single‐Cell Transcriptomics Reveals FLS2‐Dependent Hypoxia Signaling and ERF13‐Mediated Transcription During flg22‐Triggered Immunity

Advanced Science, EarlyView.
This study employs sc‐RNA sequencing, genetics, and phenotyping to systematically map the cell‐type‐specific immune responses triggered by flg22. It reveals FLS2‐dependent transcriptional reprogramming in epidermal and mesophyll cells, and uncovers crosstalk between immune and hypoxia signaling pathways.
Yaping Zhou, Aizhi Qin, Mengfan Li, Qianli Zhao, Luyao Kong, Lulu Yan, Chunyang Li, Hao Liu, Yinpeng Zhang, Jiani Long, Mengyu Liao, Mengmeng Zhou, Xiaoli Fan, Baozhen Wang, Wenxuan Kang, Shui Wang, Zhixin Liu, Xuwu Sun   +17 more
wiley   +1 more source

Парадоксалната българска рецепция на Библията през епохата на Възраждането

Slavia Meridionalis, 2016
Paradoxical Bulgarian reception of the Bible during the National Revival This paper is focused on the difficulties that Bulgarian reception of the Bible encountered in nineteenth century – the lack of older canonical translations and the opposition of ...
Николай [Nikolaĭ] Аретов [Aretov]
doaj   +1 more source

Left Transforming into Right: The Adoption and Interpretation of the Ideas of the Fluxus Movement in Lithuania in the Second Half of the 20th Century

Lietuvos Istorijos Studijos, 2022
The article examines how the ideas of the left-wing Fluxus movement were accepted and interpreted in Lithuania in the second half of the 20th century.
Dovilė Zubavičiūtė
doaj   +1 more source

Diversity Patterns of Domestic Herbivore Viruses in China Reveal Transmission Dynamics with Disease Management Implications

Advanced Science, EarlyView.
This study performs pan‐viromic profiling of 14,529 samples from 5,710 domestic herbivores across five Chinese provinces, establishing the DhCN‐Virome (1,085,360 viral metagenomes). It reveals species/sample‐specific viromic signatures and cross‐species transmission dynamics, aiding unified disease control.
Yue Sun, Yong Li, Bagen Temur, Yuanqing Lin, Yuhang Liu, Le Yi, Zheng Sun, Gang Zhang, Jun Li, Yu Guo, Linchuan Li, Jinshan Cai, Wenliang Tian, Gen Meng, Lingling Jiang, Min Fang, Fuying Ding, Xuezhang Zhou, Changchun Tu, Biao He   +19 more
wiley   +1 more source

From the Patrimonial to the Civic Standard of Music for All: The Transformations of Musical Institutions in Nineteenth-Century Bohemia and the Problems of Their Music-Historical Interpretation

Arti Musices, 2023
The topic of institutionalisation of musical life in the nineteenth century invites a new perspective on the transformation processes in multinational Austria.
Tomáš Slavický
doaj   +1 more source

NK Cell Activation by Platinum Boosts Immunotherapy in HR+/HER2− Breast Cancer

Advanced Science, EarlyView.
Multi‐omics and single‐cell analyses identify activated NK cells as key mediators of anti‐PD‐(L)1 response in HR+/HER2− breast cancer. Platinum chemotherapy enhances NK cell cytotoxicity through NF‐κB–associated signaling, synergizing with immunotherapy and providing a rationale for combination treatment.
Yi‐Yu Chen, Yi‐Fan Zhou, Xuan Qi, Ya‐Xin Zhao, Tong Fu, Xi Jin, Minhong Shen, Yi‐Zhou Jiang, Zhi‐Ming Shao   +8 more
wiley   +1 more source

Conflicts on the national confessional ground in the Armed Forces of Ukraine and measures for their prevention

Українське Pелігієзнавство, 1997
National revival is a process of forming a national consciousness that appears as the unity of the national psyche and national ideology. An important element of national consciousness is the national idea.
O. Utkin
doaj   +1 more source

DOTA‐grafted Cationic Polymers Behaving as Powerful Macromolecular Resistance‐reversal Agents (MRRAs) Combating Against New Delhi Metallo‐β‐lactamase (NDM)‐producing Bacteria

Advanced Science, EarlyView.
Two macromolecular resistance‐reversal agents (MRRAs)—linear (MRRAL) and nanostructured (MRRAN) polymers were fabricated by integrating DOTA motifs into tunable polycationic scaffolds. MRRAs exhibit superior antibacterial potency once combined with meropenem (MEM) through (i) bacterial membrane disruption via localized cationic charge and ...
Ruixue Wang, Jian Zhang, Yun li, Liping Qiao, Zhuorui Dong, Dandan Cui, Peirong Bai, Liping Li, Bing Cao, Ruiping Zhang   +9 more
wiley   +1 more source