Results 41 to 50 of about 2,987,527 (311)
National Energy Security: Implications for National Energy Policy [PDF]
The Environmental and Energy Study Institute and Senator Susan Collins (R-ME) co-hosted a Congressional briefing to examine the nation's current energy system and its vulnerabilities, as well as some of the steps and solutions to providing the nation and
Amy Brooks
core
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
THE ENVIRONMENTAL SECURITY, A NATIONAL SECURITY DIMENSION [PDF]
In the paper, the author approaches a topical issue, namely the issue of the environmental security as a dimension of the state‟s national security. Starting from a distinct approach of the security concept, in general, and of the national security as ...
Catalin PEPTAN
doaj
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
The impact of the economy condition on the economic and national security [PDF]
The syntagma 'national security', per se, points to the vital role that belongs to it in safeguarding the state. It is the foundation without which no society could develop economically, culturally, socially, and militarily.
Talijan Miroslav +2 more
doaj +1 more source
COMPREHENSIVE NATIONAL SECURITY: CONTEMPORARY DISCOURSE
National security has evolved both into a discipline of study and a sphere of policy application. It is a commonly used phrase in strategic literature and international statecraft.
Ehsan Mehmood Khan
doaj +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
THE CONCEPT OF «NATIONAL SECURITY» WITHIN THE CATEGORICAL FRAMEWORK OF PUBLIC ADMINISTRATION
The article examines the concept of «national security» within the categorical framework of public administration, highlighting the absence of a universally accepted definition of «national security» and its role in public administration.
Liliia Muntian
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source

