Results 141 to 150 of about 25,589 (191)

Transcriptomic and metabolomic analyses reveal that lobeglitazone ameliorates hepatic steatosis in rats concurrent with regulation of mitochondrial pyruvate metabolism

British Journal of Pharmacology, EarlyView.
Background and Purpose Lobeglitazone is a thiazolidinedione and PPARγ agonist that improves metabolic parameters and hepatic steatosis, but its mechanisms are not fully understood. This study investigated the effects of lobeglitazone on hepatic transcriptomic and metabolic profiles in a rat model of obesity and Type 2 diabetes mellitus.
Hyekyung Yang, Su Young Son, Youngmi Song, Hyewon Choi, In‐Gu Do, Choong Hwan Lee, Cheol‐Young Park   +6 more
wiley   +1 more source

Mitogenome characterization and organellar genome evolution in achlorophyllous orchid Chamaegastrodia shikokiana Makino & F.Maek. (Orchidaceae). [PDF]

BMC Plant Biol
Kim YK, Kim HT, Kim JS, Song JH.
europepmc   +1 more source

Adipocyte‐Derived Palmitic Acid Promotes Breast Cancer Malignancy via ZDHHC15‐Mediated S‐Palmitoylation of PPARγ

Cancer Science, EarlyView.
Adipocyte‐derived palmitic acid induces ZDHHC15‐mediated PPARγ S‐palmitoylation at Cys159, triggering its proteasomal degradation and promoting breast cancer malignancy with rosiglitazone resistance. Inhibition of PPARγ S‐palmitoylation by 2‐bromopalmitate suppresses breast cancer progression and synergistically enhances rosiglitazone efficacy ...
Geon Ho Moon, Min Young Lee, Jiwon Koh, Ki Yong Hong, Junji Fukuda, Sung Joon Kim, Yang‐Sook Chun   +6 more
wiley   +1 more source

Prophages in Skin Pathogens: From Virulence to Therapy. [PDF]

Pathogens
Karthikeyan A, Javaid A, Charway GNA, Tabassum N, Kim TH, Kim YM, Jung WK, Khan F.   +7 more
europepmc   +1 more source

How Do LLMs See Charts? A Comparative Study on High‐Level Visualization Comprehension in Humans and LLMs

Computer Graphics Forum, EarlyView.
Abstract Designers often create visualizations to achieve specific high‐level analytical or communication goals. These goals require people to extract complex and interconnected data patterns. Prior perceptual studies of visualization effectiveness have focused on low‐level tasks, such as estimating statistical quantities, and have recently explored ...
Hyotaek Jeon, Hyunwook Lee, Minjeong Shin, Tapendra Pandey, Joohee Kim, Shinwook Seon, Daeun Jeong, Sungahn Ko, Ghulam Jilani Quadri   +8 more
wiley   +1 more source

Phylogenetic Diversity and Community Assembly of Vascular Plants Along Environmental Gradients in the Western Pamir-Alay: A Case Study From Surkhandarya Province, Southern Uzbekistan. [PDF]

Ecol Evol
Ibragimov A, Karimov B, Juraev Z, Makhmudjanov D, Baasanmunkh S, Oh A, Tojibaev KS, Choi HJ.   +7 more
europepmc   +1 more source

A revised classification system of the marronoid clade of spiders (Araneae), based on dense sampling phylogenomics and comparative morphology

Cladistics, EarlyView.
Abstract The marronoid clade is a globally distributed, ecologically diverse group of spiders. It is an important faunal component in both natural and synanthropic environments, and even found in aquatic and extreme habitats such as desert salt flats. The systematics of the marronoid clade has been notoriously unstable due to the widespread character ...
Jonas O. Wolff, Michael B. J. Kelly, Franklyn Cala‐Riquelme, Jacob A. Gorneau, Katherine O. Montana, Helen M. Smith, Phil J. Sirvid, Cor J. Vink, Lauren A. Esposito, Martín J. Ramírez, Charles E. Griswold   +10 more
wiley   +1 more source

Oxidative aging facilitates biological barrier penetration of polyethylene microplastics, amplifying systemic lipotoxicity in aquatic species. [PDF]

Part Fibre Toxicol
Kim Y, Lee H, Lee E, Kim YH, Oh CK.
europepmc   +1 more source

Identifying the exposure of taxonomic, functional, and phylogenetic diversity of steppe birds to renewable energy development

Conservation Biology, EarlyView.
Abstract Biodiversity is globally threatened by human impacts, including land‐use transformation and climate change, which has prompted a rapid transition from fossil fuels to cleaner energy sources, such as photovoltaic (PV) energy. However, utility‐scale PV plants require vast areas and can lead to conflicts with biodiversity conservation, making ...
Pablo Medrano‐Vizcaíno, François Mougeot, Beatriz Arroyo, Gerard Bota, David Giralt, Laura Maeso‐Pueyo, Carlos A. Martín, Manuel B. Morales, Pedro P. Olea, Juan Traba, Ana Benítez‐López   +10 more
wiley   +1 more source

Critical Knowledge Gaps for Shellfish Allergies: Insights from Global Market Presence and Trade of Shellfish. [PDF]

Foods
Stanic-Vucinic D, Radomirovic M, Wu X, Stojadinovic M, Cirkovic Velickovic T.   +4 more
europepmc   +1 more source