Results 101 to 110 of about 842,239 (302)

11 March 2004 and its aftermath [PDF]

open access: yes
Face aux attaques terroristes, la bibliothèque nationale d\u27Espagne a mis en place des mesures de sécurité. Néanmoins, ces dernières années, la bibliothèque a assoupli son système pour l\u27ouvrir plus aux usagers.
Raldúa Martín, Eduardo V.
core   +1 more source

A Soft, Flexible Implant for Wireless Photothermal–Pyroelectric Neurostimulation

open access: yesAdvanced Science, EarlyView.
A replication strategy is used to enlarge the exposed surface area of barium titanate within flexible films with embedded carbon nanotubes, enabling efficient photothermal‐pyroelectric stimulation. Polar crystalline nanosheets show superior performance in guiding neural progenitor cells toward neuronal differentiation.
Jiang Wu   +7 more
wiley   +1 more source

French National Protocol for Diagnosis and Care of Calpainopathy (LGMD R1/LGMD D4): consensus guidelines for clinical practice

open access: yesOrphanet Journal of Rare Diseases
Background Calpainopathies, including limb-girdle muscular dystrophy recessive type 1 (LGMD R1) and the rare dominant type 4 (LGMD D4), are genetic neuromuscular disorders caused by pathogenic variants in the CAPN3 gene, which encodes calpain-3, a muscle-
Gianmarco Severa   +16 more
doaj   +1 more source

Synchrotron XRF Imaging Reveals Manganese Accumulation in the Golgi and Post‐Synapses of Neurons and Enhanced Uptake in Astrocytes

open access: yesAdvanced Science, EarlyView.
Despite widespread exposure, the mechanisms of manganese neurotoxicity remain poorly understood. Using correlative cryogenic fluorescence and synchrotron X‐ray fluorescence imaging techniques, we show that the Golgi apparatus is the primary accumulation site for manganese in both neurons and astrocytes, and that manganese targets the neuronal ...
Ines Kelkoul   +12 more
wiley   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

open access: yesAdvanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård   +19 more
wiley   +1 more source

France and the Community of Six: The Schuman Declaration to the Treaties of Rome [PDF]

open access: yes, 2015
This paper investigates France’s role during the first decade of European integration, and in particular the initiatives of Jean Monnet and Robert Schuman which led to the creation of the European Communities.
Gagnon, Daniel
core   +1 more source

Glomage: A Multimodal Platform for High‐Content Morphological and RNA Profiling of Glomeruli in Zebrafish and Mouse Models

open access: yesAdvanced Science, EarlyView.
Understanding how glomeruli, the kidney's filtration units, function in intact tissue remains challenging. Glomage enables rapid 3D imaging and quantitative analysis of entire glomeruli from zebrafish larvae and mice. This approach allows scalable cell quantification and detection of structural changes, advancing kidney disease research and ...
Maximilian Schindler   +4 more
wiley   +1 more source

Traitement mécanique de volumes importants de terres infestées par des rhizomes de renouée du Japon : technique par criblage-concassage [PDF]

open access: yesSciences, Eaux & Territoires, 2019
Confrontée au manque de filière de traitement de gros volumes de matériaux infestés par des rhizomes de renouée du Japon, la Compagnie nationale du Rhône a développé une technique très efficace pour neutraliser immédiatement les terres infestées.
MOIROUD, Christophe   +2 more
doaj  

Robotized FSW – Evolution of forces and torque with nonlinear welds [PDF]

open access: yes, 2014
The main purpose of the article is to study the evolution of the welding forces and torque with non-straight welding path. The main studies performed on forces and torque are usually done on plane straight welding path when the processing parameter are ...
ABBA, Gabriel   +6 more
core   +2 more sources

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon   +21 more
wiley   +1 more source

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