Results 131 to 140 of about 583,563 (410)

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

The Cross-Section of Interbank Rates: A Nonparametric Empirical Investigation [PDF]

open access: yes, 2012
This paper analyzes the distribution of lending and borrowing credit spreads in the European interbank market conditional on main features of banks such as their size, operating currency and nationality.
Iori, G., Kapar, B., Olmo, J.
core  

NATIONALISM AND THE NATIONAL MYTH

open access: yesЕтноАнтропоЗум/EthnoAnthropoZoom, 2005
All national ideologies are based on a single fundamental idea, a single ideological burden, which creates the nucleus of the national myth. This idea, in reference to the Greek national myth, is “the tribal invincibility of the genus” or “the continuance of the nation from ancient times to this day”.
openaire   +3 more sources

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

open access: yesMolecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita   +1 more
wiley   +1 more source

Strictosamide promotes wound healing through activation of the PI3K/AKT pathway

open access: yesHeliyon
Nauclea officinalis, as a Chinese medicine in Hainan province, had the effect of treating lower limb ulcers, burn infections. In this paper, we studied the effect of Strictosamide (STR), the main bioactive compound in Nauclea officinals, on wound healing
Gu-xu Ming   +8 more
doaj  

Learning from development of a third-party patient-oriented application using Australian national personal health records system [PDF]

open access: yesarXiv, 2017
Large-scale national level Personal Health Record (PHR) has been implemented in Australia. However, usability, data quality and poor functionalities have resulted in low utility affecting enrollment and participation rates by both patients and clinicians alike.
arxiv  

Culture, nationality and demographics in ultimatum games [PDF]

open access: yes
We use experimental data collected in Russia and in the United States using a simple ultimatum game to evaluate two alternative hypotheses that may account for previously observed behavior in multinational experiments.
Anabela Botelho   +2 more
core  

Natio et gens: Venice biennale 2009 [PDF]

open access: yes, 2010
The following is an informal reflection on the changing place of nationality and national consciousness in cultural life with reference to last year’s Biennale.
Broadhurst, S, Harvey, N
core   +1 more source

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