Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Evaluating the Impact of Demographic Factors on Subject-Independent EEG-Based Emotion Recognition Approaches. [PDF]
Douglas N, Oosterhuis M, Valderrama CE.
europepmc +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Access to Specialized Medical Training in Spain and Determinants of Failure in the National Entrance Examination: Econometric Modeling Study. [PDF]
Diaz-Fernandez M +2 more
europepmc +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Examining Japanese laypeople's nationality preferences for physicians: a nationwide study. [PDF]
Fujikawa H +4 more
europepmc +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Optimizing board structure for ESG integrity: Nonlinear size effects and diversity moderation on greenwashing. [PDF]
Yu J, Hwang YS.
europepmc +1 more source
The Literary Culture of Russian-Speaking Israel. Disputes Around The “Nationality” of Literature
Agnieszka Lenart
openalex +2 more sources
Lifestyle Practices among Students of Different Nationality in a Selected University
B Sulochana, Linu Sara George
openalex +1 more source

