Results 241 to 250 of about 82,358 (306)

Disruption of the SNRPF–DDX24–E2F4 Feedback Loop Uncouples Splicing and Transcriptional Regulation to Suppress Ovarian Cancer Progression

Advanced Science, EarlyView.
This study identifies SNRPF as a critical oncogenic driver in ovarian cancer. By regulating a self‐sustaining SNRPF–DDX24–E2F4 feedback loop through intron retention and nonsense‐mediated decay, SNRPF couples RNA splicing with transcriptional regulation to promote tumor progression.
Yingwei Li, Zhongshao Chen, Qianqian Gao, Yuehan Gao, Ning Yang   +4 more
wiley   +1 more source

Distribution, abundance and ecological associations among two species of native mussels (<i>Gonidea angulata</i> and <i>Margaritifera falcata</i>) and one invasive clam species (<i>Corbicula fluminea</i>) in the Columbia River Basin, North America. [PDF]

Aquat Sci
Neal NG, Bollens SM, Maine AN, Counihan TD, Rollwagen-Bollens G.   +4 more
europepmc   +1 more source

Glomage: A Multimodal Platform for High‐Content Morphological and RNA Profiling of Glomeruli in Zebrafish and Mouse Models

Advanced Science, EarlyView.
Understanding how glomeruli, the kidney's filtration units, function in intact tissue remains challenging. Glomage enables rapid 3D imaging and quantitative analysis of entire glomeruli from zebrafish larvae and mice. This approach allows scalable cell quantification and detection of structural changes, advancing kidney disease research and ...
Maximilian Schindler, Tim Lange, Sophia‐Marie Bach, Soeren S. Lienkamp, Nicole Endlich   +4 more
wiley   +1 more source

Improved ecological risk assessment of phenol in sediments via species sensitivity distribution and equilibrium partitioning method using water toxicity data. [PDF]

Sci Rep
Park S, Lee SJ, Park JW, Jeong HJ, Yeom DH, Kim J.   +5 more
europepmc   +1 more source

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

Advanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon, Mireille Elodie Tsitokana, Ugo Guy Alenda, Yen‐Ling Lian, Clémentine Eva Philibert, Mathieu Oosterlaken, Marta Cimadevila, Gaëlle Dudon, Jessica Monnic, Salomé Roux, Julie Bessié, Séverine Diem, Franck Vandermoere, Laurent Prézeau, Patrick Chames, Julie Kniazeff, Sylvie Claeysen, Anaïs Menny, Jean‐Philippe Pin, Véronique Perrier, Jianfeng Liu, Philippe Rondard   +21 more
wiley   +1 more source

Seedless One‐Pot Synthesis of Colloidal InAs Quantum Dots Enabling a High‐Accuracy Photoplethysmography Oximeter

Advanced Science, EarlyView.
A real‐time, non‐contact photoplethysmography (PPG) system based on InAs colloidal quantum dots (CQDs) synthesized via a seedless injection synthesis is demonstrated. The measured oxygen saturation shows considerable agreement with commercial PPG devices.
Beom Kwan Kim, Seungin Jee, Yongnam Ahn, In‐Suh Lee, Dongeon Kim, Seongchong Park, Yujin Jung, In‐Ho Bae, Se‐Woong Baek   +8 more
wiley   +1 more source

New Hybrid Combination for Local Crucian Carp Germplasm Improvement: Dongting Lake Crucian Carp (♀) × Hefang Crucian Carp (♂). [PDF]

Int J Mol Sci
Shao L, Li H, Guo H, Zhou Y, Luo K, Li W, Wang C, Wang J, Guo L, Liu Q, Qin Q, Shen Z, Liu S.   +12 more
europepmc   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Functional diversity of fish in the Yuan-Red River: Role of species turnover and trait shifts. [PDF]

iScience
Huang XX, Yang AL, Kang B, He KJ, Mei XH, Hu WX, Lin HD.   +6 more
europepmc   +1 more source

Invasive Fishes Interact With Temperature to Reshape Community Size Structure Across Climatic Zones. [PDF]

Glob Chang Biol
Rocha BS, Arranz I, Giacomini HC, Perkins DM, Salvador GN, Novaes JLC, Sánchez-Botero JI, Agostinho AA, Pompeu PS, Menezes RF, Lustosa-Costa SY, Ramos TPA, Attayde JL, da Costa Goldbaum RS, Argillier C, Gurgel-Lourenço RC, Pinto LM, Pessali TC, Rodríguez-Pérez MJ, Saito VS.   +19 more
europepmc   +1 more source